4-Fluorobenzoic Acid CAS 456-22-4

1. 4-Fluorobenzoic acid serves as a key intermediate for synthesizing pharmaceuticals and agrochemicals, including antifungal agents like flumorph and various hydrazone derivatives with antimicrobial and antituberculosis activity .
2. 4-Fluorobenzoic acid CAS 456-22-4 is utilized to produce Schiff bases with DPPH radical scavenging activity for antioxidant research and in high-resolution charge density studies .
3. 4-Fluorobenzoic acid is employed as a versatile building block for preparing 4-fluorobenzoyl chloride and other fluorinated intermediates for drug development .

1. Store 4-Fluorobenzoic acid in a tightly sealed container in a cool, dry, well-ventilated place at room temperature (below 15°C in a dark place), away from oxidizing agents .
2. Keep 4-Fluorobenzoic acid CAS 456-22-4 strictly separated from strong oxidizing agents and protect from moisture to prevent decomposition .
3. Handle 4-Fluorobenzoic acid using appropriate personal protective equipment including chemical-resistant gloves and safety goggles, and avoid breathing dust .

1. Isolate the spill 4-Fluorobenzoic acid CAS 456-22-4 area, wear suitable protective equipment including dust mask, and sweep up solid 4-Fluorobenzoic acid into sealed, labeled containers without creating dust .
2. Prevent spilled 4-Fluorobenzoic acid from entering drains or waterways, as the compound is harmful to aquatic life .
3. Personnel cleaning 4-Fluorobenzoic acid spills must dispose of waste according to local environmental regulations and ensure contaminated clothing is washed before reuse .

1. 4-Fluorobenzoic acid causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) with GHS signal word "Warning" .
2. 4-Fluorobenzoic acid CAS 456-22-4 is harmful if swallowed (H302) and has a vapor pressure of 0.019 mm Hg .
3. 4-Fluorobenzoic acid has a flash point of >110°C, and combustion produces toxic fumes including carbon monoxide and hydrogen fluoride .