Alpha-Chloro-o-fluorotoluene CAS 345-35-7

1. Alpha-Chloro-o-fluorotoluene is primarily used as a key intermediate in organic synthesis, particularly in the pharmaceutical industry for constructing drug molecules with specific biological activities . Its structure allows for further chemical modifications to achieve desired properties .
2. Alpha-Chloro-o-fluorotoluene CAS 345-35-7 serves as a versatile building block for creating more complex molecules in the production of agrochemicals and other specialty chemicals .
3. Applications of Alpha-Chloro-o-fluorotoluene also include its use in developing novel crop protection agents and biological pesticides .

1. Store Alpha-Chloro-o-fluorotoluene in a tightly sealed container under inert gas (e.g., argon) in a cool, dry, well-ventilated area away from heat, sparks, and open flames . Recommended storage is refrigerated (2-8°C) or in a cool, dark place below 15°C, protected from light and moisture .
2. Keep Alpha-Chloro-o-fluorotoluene strictly away from moisture, strong oxidizing agents, alcohols, bases, and amines, as these materials are incompatible . Do not store in steel containers .
3. Always Alpha-Chloro-o-fluorotoluene CAS 345-35-7 use appropriate personal protective equipment (PPE) including butyl rubber gloves, tightly fitting safety goggles with faceshield, and protective clothing; use only with explosion-proof equipment and adequate ventilation (fume hood) . Ground and bond containers when transferring to prevent electrostatic discharge .

1. Immediately isolate the spill area, eliminate all ignition sources, and provide ventilation. Contain Alpha-Chloro-o-fluorotoluene using inert, non-combustible absorbent material (e.g., dry sand or earth) and absolutely avoid contact with water . A vapor-suppressing foam may be used to reduce vapors .
2. Carefully collect Alpha-Chloro-o-fluorotoluene CAS 345-35-7 using non-sparking tools or an explosion-proof vacuum cleaner, and place it into sealed, labeled corrosion-resistant chemical waste containers for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear full chemical-protective equipment including self-contained breathing apparatus (SCBA) during cleanup. Alpha-Chloro-o-fluorotoluene is classified for transport (UN2920 or UN1760, Hazard Class 8/3, PG II) and requires hazardous waste disposal . Prevent entry into drains or waterways .

1. Alpha-Chloro-o-fluorotoluene is classified with GHS signal word "Danger" (H226, H314, H318) as a flammable liquid (flash point 57°C/135°F) and corrosive substance causing severe skin burns, serious eye damage, and is a lachrymator (tear gas agent) . Inhalation may cause severe respiratory tract irritation, chemical burns, and delayed lung edema .
2. Alpha-Chloro-o-fluorotoluene reacts with water, and thermal decomposition or combustion produces toxic and corrosive fumes including hydrogen chloride, hydrogen fluoride, carbon monoxide, and carbon dioxide . Contact with metals may evolve flammable hydrogen gas . It has a boiling point of 86°C/40mmHg and density of 1.216 g/mL .
3. Always consult Alpha-Chloro-o-fluorotoluene CAS 345-35-7 the specific Safety Data Sheet (SDS) for Alpha-Chloro-o-fluorotoluene for complete hazard information, first-aid procedures (P305+P351+P338+P310 for eyes, P301+P330+P331 for ingestion, P303+P361+P353 for skin, P304+P340+P310 for inhalation), and handling instructions; precautionary statements include P210 (keep away from heat/sparks/open flames), P260 (do not breathe vapors), P280 (wear protective gloves/eye protection), and P403+P233 (store in well-ventilated place, keep container tightly closed) .