Bromocyclohexane CAS 108-85-0

1. Bromocyclohexane is widely utilized as a versatile alkylating reagent and electrophilic building block in organic synthesis to introduce the cyclohexyl group into complex molecules for pharmaceuticals and agrochemicals . Bromocyclohexane CAS 108-85-0 is particularly important in the preparation of Grignard reagents (cyclohexylmagnesium bromide) for carbon-carbon bond formation .
2. The compound serves as a valuable intermediate in polymer chemistry, where Bromocyclohexane CAS 108-85-0 acts as a comonomer to enhance material properties such as thermal stability, and is employed in material science research for developing flame-retardant compounds due to its bromine content .
3. Applications of Bromocyclohexane also include its use as a solvent in chemical reactions, in environmental studies to investigate the behavior of halogenated compounds, and as a model substrate for studying reaction mechanisms (E2 elimination, alkyl-alkyl cross-coupling) .

1. Store Bromocyclohexane in a tightly sealed container in a cool, dry, and well-ventilated place away from heat and ignition sources. Recommended storage conditions include refrigeration at 0-8°C or a cool, dark place below 15°C .
2. Keep Bromocyclohexane away from strong bases (incompatible materials) and oxidizing agents. It is stable under normal conditions but may accumulate electrostatic charge; containers should be grounded and kept upright when opened .
3. Always Bromocyclohexane CAS 108-85-0 use appropriate personal protective equipment (PPE) including chemical-resistant gloves (fluorinated rubber recommended), safety glasses with side-shields, and protective clothing. Handle only with adequate ventilation or in a fume hood and avoid breathing vapors .

1. Immediately isolate the spill area, eliminate all ignition sources, and ensure adequate ventilation. Contain Bromocyclohexane using inert, non-combustible absorbent material (e.g., dry sand) and prevent entry into drains or waterways as it is toxic to aquatic organisms .
2. Carefully collect Bromocyclohexane CAS 108-85-0 using an electrically protected vacuum cleaner or by wet-brushing with spark-proof tools into a sealed, labeled chemical waste container for proper disposal according to local regulations .
3. Personnel must wear suitable PPE including self-contained breathing apparatus (SCBA) if necessary during cleanup. Vapors are heavier than air and may accumulate in low areas to form explosive concentrations .

1. Bromocyclohexane is classified as a combustible liquid (H227, flash point 62-63°C closed cup) with GHS signal word "Warning". It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) . NFPA health rating is 1 (irritation only) .
2. Bromocyclohexane has a boiling point of 166-167°C, melting point -57°C, and density of approximately 1.33 g/mL. It is insoluble in water, has a vapor density of 5.62 (vs air), and is toxic to aquatic life with LC50 (guppy) of 12 mg/L/96h . Thermal decomposition produces toxic and irritating fumes including carbon oxides and hydrogen bromide gas .
3. Always Bromocyclohexane CAS 108-85-0 consult the specific Safety Data Sheet (SDS) for Bromocyclohexane for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P303+P361+P353 for skin), and handling instructions. Precautionary statements include P210 (keep away from heat/sparks/open flames), P240 (ground/bond container), and P280 (wear protective gloves/eye protection) . UN classification is UN1993, Hazard Class 3, Packing Group III .