Suberic Acid CAS 505-48-6

1. Suberic acid is primarily used as a key monomer in polymer production for synthesizing polyesters and polyamides, which are used in textiles and plastics to enhance durability and flexibility . Suberic acid CAS 505-48-6 is also utilized in the preparation of reduction-sensitive micelles for targeted drug delivery, particularly in anticancer therapy .
2. The compound serves as an important intermediate in pharmaceutical synthesis, with its derivatives used in drug formulations providing therapeutic benefits, especially in anti-inflammatory and analgesic medications . Suberic acid CAS 505-48-6 is also employed in the synthesis of antimalarial aminopyridine solid forms .
3. Applications of Suberic acid also include its use as a food additive for flavor enhancement and preservation , in cosmetic formulations as a moisturizer and stabilizer , and in the development of biodegradable eco-friendly materials . It is also used in the fluorescent detection of amidinium-carboxylate formation .

1. Store Suberic acid in a tightly sealed container in a cool, dry, and well-ventilated place. Recommended storage conditions include refrigeration at 0-8°C or a cool, dry place protected from light .
2. Keep Suberic acid away from strong oxidizing agents, reducing agents, and bases, as these materials are incompatible and may cause hazardous decomposition . Avoid formation of dust and aerosols .
3. Always Suberic acid CAS 505-48-6 use appropriate personal protective equipment (PPE) including chemical-resistant gloves (nitrile rubber recommended, minimum thickness 0.11 mm) , safety glasses with side-shields , and protective clothing when handling Suberic acid to avoid skin, eye, and respiratory contact .

1. Immediately isolate the spill area, use personal protective equipment, and avoid dust formation. Contain Suberic acid using inert, non-combustible absorbent material and prevent entry into drains or waterways .
2. Carefully sweep up or shovel the spilled Suberic acid without creating dust and place the collected material into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel Suberic acid CAS 505-48-6 must wear suitable PPE, including self-contained breathing apparatus if necessary, during cleanup . Suberic acid is considered non-hazardous for transport (not a dangerous good) by DOT, IATA, and IMDG regulations .

1. Suberic acid is classified with GHS signal word "Warning". It causes skin irritation (H315), serious eye irritation (H319 - Category 2A), and may cause respiratory irritation (H335) . Acute oral LD50 in rats is >2000 mg/kg, and skin irritation tests in rabbits show no significant irritation .
2. Suberic acid has a flash point of 210°C (closed cup) and is combustible. Thermal decomposition produces toxic and irritating fumes including carbon oxides (CO, CO₂) . It has a melting point of 140-144°C and boiling point of 230°C . It is soluble in water (1.6 g/L at 20°C, pH 3.2), DMSO, and methanol, slightly soluble in ether, and insoluble in chloroform .
3. Always Suberic acid CAS 505-48-6 consult the specific Safety Data Sheet (SDS) for Suberic acid for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P302+P352 for skin, P304+P340 for inhalation), and handling instructions. Precautionary statements include P260 (do not breathe dust), P280 (wear protective gloves/eye protection), and P405 (store locked up) .