Ethyl P-nitrobenzoate CAS 99-77-4

1. Ethyl p-nitrobenzoate is a key intermediate for synthesizing pharmaceuticals, including the local anesthetic benzocaine (anesthesine) and other drugs like tetracaine .
2. Ethyl p-nitrobenzoate CAS 99-77-4 serves as a building block in organic synthesis, where the nitro group can be reduced to an amine and the ester group can be further modified .
3. Ethyl p-nitrobenzoate also finds use as an intermediate in the production of insecticides and as a sunscreening agent .

1. Store Ethyl p-nitrobenzoate in a tightly sealed container in a cool, dry, well-ventilated place, away from heat sources .
2. Keep Ethyl p-nitrobenzoate CAS 99-77-4 strictly separated from strong oxidizing agents, reducing agents, and bases to prevent unwanted reactions .
3. Handle Ethyl p-nitrobenzoate using appropriate personal protective equipment including gloves and safety goggles, and avoid forming or breathing dust .

1. Isolate the spill Ethyl p-nitrobenzoate CAS 99-77-4 area and avoid dust formation; contain Ethyl p-nitrobenzoate using clean sweeping or shoveling into sealed, labeled containers .
2. Prevent Ethyl p-nitrobenzoate from entering drains or waterways during cleanup .
3. Personnel cleaning Ethyl p-nitrobenzoate spills must wear suitable protective equipment and dispose of waste according to local environmental regulations .

1. Ethyl p-nitrobenzoate is harmful if swallowed (oral LD50 rat: 2660 mg/kg; mouse: 250 mg/kg ipr) .
2. Ethyl p-nitrobenzoate CAS 99-77-4 may decompose under fire conditions to produce toxic fumes including nitrogen oxides and carbon monoxide .
3. Ethyl p-nitrobenzoate is classified with GHS signal word "Warning" and safety phrases S22 and S24/25 recommend avoiding dust inhalation and skin contact .