Phenyl Bromoacetate CAS 620-72-4

1. Phenyl bromoacetate is primarily used as an alkylating reagent and versatile building block in organic synthesis, particularly in the preparation of heterocyclic compounds such as triazoles and thiazolidinones . It serves as a key intermediate in pharmaceutical research for synthesizing cannabinoid CB1 receptor antagonists and selective aldose reductase inhibitors .
2. Phenyl bromoacetate CAS 620-72-4 may be employed in the synthesis of complex natural product fragments, such as the A-ring of cylindrospermopsin, and in the preparation of various 4-thiazolidinone derivatives with potential biological activities .
3. Applications of Phenyl bromoacetate also include its use in the development of specialized industrial products like anti-sticking lining cloth and super-hydrophobic fabric coatings , as well as a preservative in paints and metalworking fluids .

1. Store Phenyl bromoacetate in a tightly sealed container under an inert gas (e.g., argon) in a cool, dry, and well-ventilated place . Recommended storage is at room temperature in a cool, dark area, protected from light and moisture.
2. Keep Phenyl bromoacetate away from strong oxidizing agents, as it is incompatible with these materials, and store it in a location with good fire protection measures .
3. Always Phenyl bromoacetate CAS 620-72-4 use appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing when handling Phenyl bromoacetate to avoid skin, eye, and respiratory contact .

1. Immediately contain the Phenyl bromoacetate spill using inert, non-combustible absorbent material (e.g., sand) and prevent entry into drains or waterways. Avoid generating dust and ensure adequate ventilation .
2. Carefully sweep up or collect the spilled solid using non-sparking tools and place the contaminated material into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel Phenyl bromoacetate CAS 620-72-4 must wear suitable PPE including chemical-resistant gloves and eye protection during cleanup. Under fire conditions, decomposition products include toxic and irritating fumes such as carbon oxides and hydrogen bromide .

1. Phenyl bromoacetate is classified with a GHS "Warning" signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). It is harmful if swallowed, inhaled, or in contact with skin .
2. Phenyl bromoacetate has a flash point of 113°C (235°F) and is considered a combustible liquid. It is soluble in ethanol and ether but insoluble in water . While not classified as a dangerous good for transport by some regulations, it should be handled with care .
3. Always consult Phenyl bromoacetate CAS 620-72-4 the specific Safety Data Sheet (SDS) for Phenyl bromoacetate for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P302+P352 for skin), and handling instructions. Precautionary statements include P261 (avoid breathing dust), P280 (wear protective gloves/eye protection), and P304+P340 (if inhaled) .