3-Bromo-2-fluoronitrobenzene CAS 58534-94-4

1. 3-Bromo-2-fluoronitrobenzene is a halogenated aromatic compound primarily used as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty organic compounds .
2. 3-Bromo-2-fluoronitrobenzene serves as a versatile building block in organic synthesis for the preparation of substituted benzene derivatives, where the bromine, fluorine, and nitro groups enable selective nucleophilic aromatic substitution and cross-coupling reactions .
3. 3-Bromo-2-fluoronitrobenzene is employed in the synthesis of bioactive molecules, including kinase inhibitors and other therapeutic agents targeting various diseases .
4. Researchers utilize 3-Bromo-2-fluoronitrobenzene as a reference standard in analytical chemistry and as a starting material for the preparation of various heterocyclic compounds and functional materials .

1. 3-Bromo-2-fluoronitrobenzene must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at room temperature in a cool, dark place .
2. 3-Bromo-2-fluoronitrobenzene is classified with GHS hazard statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H332 (Harmful if inhaled), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep 3-Bromo-2-fluoronitrobenzene away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when 3-Bromo-2-fluoronitrobenzene is released .
2. Collect 3-Bromo-2-fluoronitrobenzene by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. 3-Bromo-2-fluoronitrobenzene is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, nitrogen oxides (NOx), hydrogen bromide, and hydrogen fluoride .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 3-Bromo-2-fluoronitrobenzene may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 3-Bromo-2-fluoronitrobenzene due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .