4-Aminopyridine-2-carboxylic Acid CAS 100047-36-7

1. 4-Aminopyridine-2-carboxylic acid is a heterocyclic building block primarily used in pharmaceutical research for the synthesis of bioactive compounds, including potential therapeutics for neurological disorders .
2. 4-Aminopyridine-2-carboxylic acid CAS 100047-36-7 serves as a versatile intermediate in organic synthesis for preparing pyridine derivatives, where the amino and carboxylic acid groups enable further functionalization through amidation, esterification, and coupling reactions .
3. 4-Aminopyridine-2-carboxylic acid is employed in the development of kinase inhibitors and other enzyme modulators for drug discovery programs .
4. Researchers utilize 4-Aminopyridine-2-carboxylic acid CAS 100047-36-7 as a reference standard in analytical chemistry and as a precursor for the synthesis of metal-organic frameworks (MOFs) and coordination complexes .

1. 4-Aminopyridine-2-carboxylic acid must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at room temperature in a cool, dark place .
2. 4-Aminopyridine-2-carboxylic acid CAS 100047-36-7 is classified with GHS hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas and avoiding formation of dust and aerosols .
4. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when 4-Aminopyridine-2-carboxylic acid is released .
2. Collect 4-Aminopyridine-2-carboxylic acid CAS 100047-36-7 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. 4-Aminopyridine-2-carboxylic acid is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 4-Aminopyridine-2-carboxylic acid CAS 100047-36-7 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 4-Aminopyridine-2-carboxylic acid due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .