5 6-dihydroxyindoline Hbr CAS 138937-28-7

5 6-dihydroxyindoline hbr (CAS:138937-28-7) is an important biochemical reagent.

Its main applications including:

1. 5 6-dihydroxyindoline hbr is a critical intermediate for synthesizing melanin precursors and skin whitening, hair dye related cosmetic functional raw materials.
2. 5 6-dihydroxyindoline hbr is a common building block used for preparing catecholamine analog drugs acting on the human nervous system.
3. 5 6-dihydroxyindoline hbr is an essential raw material for researching biological antioxidant reagents and nitrogen heterocyclic biological labeling molecules.

1. Keep the container tightly sealed and stored below 25°C in a dry dark environment to prevent phenolic hydroxyl oxidation and deliquescence.
2. Avoid repeated opening of the package to stop discoloration triggered by oxygen and water vapor in the ambient air.
3. Store separately from strong oxidants and strong bases to avoid phenolic salt formation and heterocyclic ring destruction.

1. Prevent inhalation of crystalline dust; equip dust masks and chemical-resistant gloves during weighing and material transfer processes.
2. This hydrobromide irritates skin, eyes and respiratory tract; flush contaminated areas with massive running water right after exposure.
3. Waste solids and waste liquid need to be handled following the disposal rules of phenolic heterocyclic hydrobromide hazardous waste.

1. Dual phenolic hydroxyl groups provide active sites for derivatization reactions such as etherification and esterification in organic synthesis.
2. The hydrobromide salt form greatly enhances water solubility compared with free base, simplifying solution configuration in reaction systems.
3. Stable indoline saturated ring structure maintains high reaction stability under mild aqueous-phase synthesis conditions.