5 6-DiMethoxyindoline CAS 15937-07-2

5 6-DiMethoxyindoline (CAS:15937-07-2) is an important biochemical reagent.

Its main applications including:

1. 5 6-DiMethoxyindoline is a core structural fragment for synthesizing dopamine receptor regulators and central nervous system related drug intermediates.
2. 5 6-DiMethoxyindoline is a common synthetic precursor for preparing natural alkaloid analogues in fine organic synthesis routes.
3. 5 6-DiMethoxyindoline is a key raw material for developing biological fluorescent probes with nitrogen heterocyclic skeletons.

1. Seal the container completely and store under 25°C in a dry dark place to prevent oxidation of the indoline saturated heterocyclic ring.
2. Reduce frequent opening of packaging to avoid oxidation discoloration caused by long-term contact with air and moisture.
3. Store apart from strong oxidants and strong mineral acids to prevent ring-opening decomposition of the indoline skeleton.

1. Avoid inhalation of solid dust; wear dust masks and chemical-resistant gloves during weighing and feeding operations.
2. 5 6-DiMethoxyindoline has mild irritant effects on skin and mucous membranes; rinse the contact site with plenty of running water once splashed into eyes or adhered to skin.
3. Waste solids and waste liquid shall be disposed according to the management standards of alkoxy nitrogen heterocyclic hazardous waste.

1. Two methoxy groups improve molecular lipophilicity and strengthen binding affinity with biological target proteins.
2. The saturated pyrrolidine ring has higher chemical stability than aromatic indole and is easy to carry out selective functional modification.
3. High-purity solid raw materials can ensure stable reaction conversion rate in the synthesis of bioactive heterocyclic compounds.