Ethyl-5-Bromo-2-carboxylate CAS 16732-70-0

Ethyl-5-Bromo-2-carboxylate (CAS:16732-70-0) is an important organic chemistry.

Its main applications including:

1. Ethyl-5-Bromo-2-carboxylate is a key bromo-ester disubstituted indole precursor for preparing high-purity indole pharmaceutical intermediates.
2. Ethyl-5-Bromo-2-carboxylate is widely used substrate for metal-catalyzed coupling reactions in fine organic synthesis.
3. Ethyl-5-Bromo-2-carboxylate is a raw material for synthesizing nitrogen-containing heterocyclic bioactive molecules and functional fine chemicals.

1. Seal tightly and store below 25°C in dry dark warehouse to avoid photodegradation of bromoindole ester structure.
2. Keep away from impact, friction and high temperature to reduce thermal decomposition risk of bromo and ester functional groups.
3. Ethyl-5-Bromo-2-carboxylate should be stored separately from strong reducing agents, strong bases and moisture to prevent debromination and ester hydrolysis reaction.

1. Avoid inhalation of crystalline dust; wear dust mask and chemical-resistant gloves during weighing and transfer.
2. Do not ingest the solid; flush exposed eyes and skin with abundant running water immediately after contact.
3. Dispose waste residues and filtrate strictly following halogenated ester hazardous waste management standards.

1. The bromo group can be easily coupled and derivatized, while the ester group supports hydrolysis and condensation for diversified indole modification.
2. The indole ring maintains stable structure under normal mild synthesis heating conditions.
3. High purity solid reduces miscellaneous impurities in pharmaceutical intermediate manufacturing routes.