5-Bromo-2 4-dichloropyrimidine CAS 36082-50-5

1. 5-Bromo-2,4-dichloropyrimidine CAS 36082-50-5 is primarily used as a key intermediate in the synthesis of pharmaceuticals, particularly for developing antiviral and anticancer agents, as well as positive allosteric modulators for GABA​B receptors .
2. 5-Bromo-2 4-dichloropyrimidine serves as a versatile building block in agricultural chemistry for synthesizing herbicides and other crop protection agents, offering effective solutions for weed control .
3. 5-Bromo-2,4-dichloropyrimidine is employed in biochemical research for synthesizing nucleoside analogs crucial for studying DNA and RNA processes and genetic mechanisms .
4. Researchers utilize 5-Bromo-2 4-dichloropyrimidine as a starting reagent for preparing pyridinepyrimidine analogs and in material science for producing specialty polymers and coatings with enhanced durability .

1. 5-Bromo-2,4-dichloropyrimidine CAS 36082-50-5 must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment at 2-8°C, protected from light and moisture .
2. 5-Bromo-2 4-dichloropyrimidine is classified as a corrosive and toxic substance (GHS hazard codes T, C) with hazard statements H301+H311+H331 (toxic if swallowed, skin contact, or inhaled), H314 (causes severe skin burns and eye damage), and H317 (may cause allergic skin reaction) .
3. Personnel must wear chemical-resistant gloves (rubber), safety goggles, face shield, and protective clothing when handling this substance, working only in well-ventilated areas such as chemical fume hoods .
4. Avoid inhalation of dust particles or vapors, prevent 5-Bromo-2 4-dichloropyrimidine contact with skin, eyes, and clothing, and wash thoroughly after handling.

1. Isolate the spill area, ensure adequate ventilation, eliminate all ignition sources, and wear full personal protective equipment including self-contained breathing apparatus when 5-Bromo-2,4-dichloropyrimidine CAS 36082-50-5 is released .
2. Collect 5-Bromo-2 4-dichloropyrimidine using non-sparking tools by sweeping or vacuuming without creating dust, or use inert absorbent materials (sand, vermiculite, universal binders), and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure, and decontaminate surfaces and equipment using appropriate methods, ensuring spilled material does not enter drains or water courses .
4. Dispose of collected 5-Bromo-2 4-dichloropyrimidine material according to local, state, and federal environmental regulations, preferably through licensed chemical destruction or controlled incineration with flue gas scrubbing .

1. 5-Bromo-2,4-dichloropyrimidine CAS 36082-50-5 is combustible with a flash point of approximately 110-113°C (230-235°F) and may decompose under fire conditions emitting toxic fumes .
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product, avoiding straight water streams that may spread the fire .
3. Firefighters 5-Bromo-2 4-dichloropyrimidine should wear self-contained breathing apparatus and full protective gear when handling burning 5-Bromo-2,4-dichloropyrimidine due to hazardous decomposition gases including carbon monoxide, carbon dioxide, nitrogen oxides (NOx), hydrogen chloride, and hydrogen bromide .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray, contain fire runoff to prevent environmental contamination, and collect contaminated fire extinguishing water separately .