5-Nitrouracil CAS 611-08-5

1. 5-Nitrouracil is primarily used as a key intermediate in drug synthesis, particularly for developing antiviral and anticancer agents by generating various drug molecules with therapeutic potential through chemical reactions.
2. 5-Nitrouracil CAS 611-08-5 serves as a biochemical reagent to study metabolic pathways and enzyme interactions, acting as a nucleotide analog to analyze DNA structure, explore gene mutation mechanisms, and investigate nucleic acid binding abilities.
3. 5-Nitrouracil is employed in pharmaceutical development as an enzyme inhibitor and thyroid antagonist, with research exploring its potential as an anti-cancer agent targeting specific tumor cells in oncology research.
4. Researchers utilize 5-Nitrouracil CAS 611-08-5 in antiviral research against respiratory system infections, in mutagenesis studies for understanding genetic mutations, and as an analytical standard for detecting related compounds in complex mixtures.

1. 5-Nitrouracil must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture, with recommended storage at 0-8°C.
2. 5-Nitrouracil CAS 611-08-5 should be kept at -20°C in a freezer for long-term storage to maintain stability, and kept away from incompatible materials such as strong oxidizing agents.
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling 5-Nitrouracil, as it causes skin irritation, serious eye irritation, and may cause respiratory irritation (H315, H319, H335).
4. Avoid formation of dust and aerosols, ensure adequate ventilation in work areas, wash thoroughly after handling, and follow safety statements S22 (Do not breathe dust) and S24/25 (Avoid contact with skin and eyes).

1. Isolate the spill area, ensure adequate ventilation, and avoid dust formation when 5-Nitrouracil is released, wearing full personal protective equipment including respirator if necessary.
2. Collect 5-Nitrouracil CAS 611-08-5 by vacuuming or sweeping without creating dust, or use inert absorbent materials, and place into suitable closed containers for disposal using spark-proof tools.
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure, clean up spills immediately using appropriate protective equipment, and prevent the product from entering drains or water courses.
4. Dispose of collected 5-Nitrouracil CAS 611-08-5 material according to local, state, and federal environmental regulations, preferably through licensed chemical destruction or controlled incineration with flue gas scrubbing.

1. 5-Nitrouracil is not classified as highly flammable but may decompose under fire conditions, with a flash point of approximately 110-227.9°C, emitting toxic fumes including nitrogen oxides, carbon monoxide, and carbon dioxide.
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product, selecting appropriate extinguishing media based on surrounding environment.
3. Firefighters 5-Nitrouracil CAS 611-08-5 should wear self-contained breathing apparatus and full protective gear when handling burning 5-Nitrouracil due to hazardous decomposition gases including nitrogen oxides, carbon monoxide, irritating and toxic fumes.
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination, and move containers from the fire area if safe to do so.