5-Methoxy-pyridin-3-ylamine CAS 64436-92-6

1. 5-Methoxy-pyridin-3-ylamine CAS 64436-92-6 is a heterocyclic building block primarily used in pharmaceutical research for the synthesis of kinase inhibitors and other bioactive compounds targeting various therapeutic areas .
2. 5-Methoxy-pyridin-3-ylamine serves as a versatile intermediate in medicinal chemistry for the preparation of pyridine-based drug candidates, including potential anticancer, antiviral, and anti-inflammatory agents .
3. In agrochemical development, 5-methoxy-pyridin-3-ylamine is employed as a precursor for the synthesis of herbicides, fungicides, and other crop protection agents .
4. Researchers utilize 5-Methoxy-pyridin-3-ylamine as a versatile synthon in organic synthesis, where the amino and methoxy groups enable selective functionalization through amidation, alkylation, and cross-coupling reactions .

1. 5-Methoxy-pyridin-3-ylamine CAS 64436-92-6 must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at -20°C for long-term stability .
2. 5-Methoxy-pyridin-3-ylamine is classified with GHS hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when 5-Methoxy-pyridin-3-ylamine is released .
2. Collect 5-Methoxy-pyridin-3-ylamine by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. 5-Methoxy-pyridin-3-ylamine CAS 64436-92-6 is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 5-Methoxy-pyridin-3-ylamine may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 5-Methoxy-pyridin-3-ylamine due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .