7-Hydroxycoumarin CAS 93-35-6

1. 7-Hydroxycoumarin (umbelliferone) is a naturally occurring coumarin derivative primarily used in biochemical research as a fluorescent probe for enzyme activity assays, particularly for detecting cytochrome P450 activity and other metabolic enzymes .
2. 7-Hydroxycoumarin CAS 93-35-6 serves as a key building block in the synthesis of fluorescent dyes, photoluminescent materials, and pharmaceutical intermediates with antioxidant, anti-inflammatory, and antimicrobial properties .
3. 7-Hydroxycoumarin is employed in cosmetic and sunscreen formulations as a UV-absorbing agent and as a component in fragrance compositions .
4. Researchers utilize 7-Hydroxycoumarin CAS 93-35-6 as a reference standard in analytical chemistry and in studies investigating coumarin metabolism, photophysics, and structure-activity relationships .

1. 7-Hydroxycoumarin must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at -20°C for long-term stability .
2. 7-Hydroxycoumarin CAS 93-35-6 is classified with GHS hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when 7-Hydroxycoumarin is released .
2. Collect 7-Hydroxycoumarin CAS 93-35-6 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. 7-Hydroxycoumarin is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 7-Hydroxycoumarin CAS 93-35-6 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 7-Hydroxycoumarin due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .