Mandelic Acid CAS 17199-29-0

1. Mandelic acid is an alpha-hydroxy acid (AHA) widely used in cosmetic and dermatological formulations for chemical peels, acne treatment, and skin rejuvenation due to its larger molecular size, which allows for slower penetration and reduced irritation compared to other AHAs .
2. Mandelic acid CAS 17199-29-0 serves as a key intermediate in the synthesis of pharmaceuticals, including cephalosporin antibiotics, antitumor agents, and chiral building blocks for asymmetric synthesis .
3. Mandelic acid is employed as a resolving agent for the separation of racemic mixtures and as a chiral derivatizing agent in analytical chemistry for enantiomeric purity determination .
4. In the food and beverage industry, mandelic acid is used as an acidulant and preservative, and in industrial applications as a precursor for the production of specialty chemicals and polymers .

1. Mandelic acid must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at room temperature in a cool, dark place .
2. Mandelic acid CAS 17199-29-0 is classified with GHS hazard statements H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation), with signal word "Danger" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep Mandelic acid CAS 17199-29-0 away from incompatible materials such as strong oxidizing agents, strong bases, and reducing agents to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when Mandelic acid is released .
2. Collect Mandelic acid CAS 17199-29-0 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent mandelic acid from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. Mandelic acid is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and irritating gases .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as Mandelic acid CAS 17199-29-0 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning Mandelic acid due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .