L-Homophenylalanine / L-Homophe-OH CAS 943-73-7

1. L-Homophenylalanine is a non-proteinogenic amino acid primarily used as a key intermediate in the synthesis of pharmaceutical compounds, including angiotensin-converting enzyme (ACE) inhibitors such as enalapril and other antihypertensive agents .
2. L-Homophe-OH CAS 943-73-7 serves as a versatile building block in medicinal chemistry for the preparation of chiral drugs, peptidomimetics, and bioactive molecules with potential therapeutic applications .
3. L-Homophenylalanine is employed in peptide synthesis to introduce homophenylalanine residues into peptides, which can enhance biological activity and metabolic stability .
4. Researchers utilize L-Homophe-OH CAS 943-73-7 as a chiral building block in asymmetric synthesis and as a reference standard in analytical chemistry for the detection and quantification of amino acid derivatives .

1. L-Homophenylalanine must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at -20°C for long-term stability .
2. L-Homophe-OH CAS 943-73-7 is classified with GHS hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when L-Homophenylalanine is released .
2. Collect L-Homophe-OH CAS 943-73-7 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. L-Homophenylalanine is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as L-Homophe-OH CAS 943-73-7 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning L-Homophenylalanine due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .