L-Hydroxyproline CAS 51-35-4

1. L-Hydroxyproline is a non-proteinogenic amino acid primarily used in biochemical research as a key component of collagen, where it contributes to the structural stability and thermal stability of the triple helix .
2. L-Hydroxyproline serves as a building block in the synthesis of collagen-based biomaterials, wound healing formulations, and tissue engineering scaffolds .
3. L-Hydroxyproline is employed in the food and cosmetic industries as a functional ingredient for skin health, promoting collagen synthesis and improving skin elasticity and hydration .
4. Researchers utilize L-Hydroxyproline as a reference standard in analytical chemistry for the detection and quantification of hydroxyproline in biological samples, which serves as a marker for collagen content and turnover .

1. L-Hydroxyproline must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; powder is stable for up to 3 years at -20°C or 2 years at 4°C .
2. L-Hydroxyproline CAS 51-35-4 is classified with GHS hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep L-Hydroxyproline away from incompatible materials such as strong oxidizing agents; for solution storage, prepare aliquots and use within 1 month at -20°C, avoiding repeated freeze-thaw cycles .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when L-Hydroxyproline is released .
2. Collect L-Hydroxyproline by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. L-Hydroxyproline is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as L-Hydroxyproline may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning L-Hydroxyproline due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .