Methyl Indole-4-carboxylate CAS 39830-66-5

Methyl indole-4-carboxylate (CAS:39830-66-5) is an important Indole compounds.

Its main applications including:

1. Methyl indole-4-carboxylate is an important indole intermediate for developing nervous system and anti-inflammatory small molecule drugs.
2. Methyl indole-4-carboxylate is a versatile substrate for Suzuki coupling, ester hydrolysis and multi-step heterocyclic construction.
3. Methyl indole-4-carboxylate is a raw material for fluorescent biological probes and nitrogen-containing optoelectronic functional materials.

1. Seal tightly and store below 25°C in dry dark warehouse to prevent photodegradation of indole skeleton.
2. Minimize repeated opening of packages to avoid oxidative discoloration from air contact.
3. Store separately from strong acids, strong alkalis and oxidizing agents to prevent ester hydrolysis.

1. Avoid inhalation of crystalline dust; wear dust mask and chemical-resistant gloves during weighing and transfer.
2. Do not ingest the solid; flush contaminated eyes and skin with plenty of running water immediately after contact.
3. Dispose waste residues and filtrate following nitrogen-containing aromatic ester hazardous waste standards.

1. Methyl ester group can be hydrolyzed to carboxyl for amidation and condensation derivatization.
2. Stable indole ring adapts to common catalytic heating and cross-coupling reaction conditions.
3. High crystal purity reduces side impurities during synthesis of bioactive indole compounds.