Sesamol CAS 533-31-3

1. Sesamol is a natural phenolic compound derived from sesame seeds, primarily used in research for its potent antioxidant properties, where it effectively scavenges free radicals and protects against oxidative stress .
2. Sesamol exhibits anti-inflammatory activity by inhibiting the production of pro-inflammatory cytokines and modulating signaling pathways such as NF-κB and MAPK .
3. Sesamol is employed in neuroprotective studies for its potential to prevent neuronal damage in conditions such as Parkinson's disease, Alzheimer's disease, and cerebral ischemia through its antioxidant and anti-inflammatory mechanisms .
4. Researchers utilize sesamol in studies of cardiovascular protection, where it demonstrates the ability to reduce lipid peroxidation, lower cholesterol levels, and protect against ischemia-reperfusion injury .

1. Sesamol must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at -20°C for long-term stability (up to 3 years) or at 4°C for up to 2 years .
2. For solution storage, prepare aliquots in tightly sealed vials and store at -80°C for up to 6 months or at -20°C for up to 1 month, avoiding repeated freeze-thaw cycles to prevent degradation .
3. Sesamol CAS 533-31-3 is classified with GHS hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
4. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas and avoiding formation of dust and aerosols .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when Sesamol is released .
2. Collect Sesamol CAS 533-31-3 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. Sesamol is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and irritating gases .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as Sesamol CAS 533-31-3 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning Sesamol due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .