2-Bromophenylacetic Acid CAS 18698-97-0

1. 2-Bromophenylacetic acid CAS 18698-97-0 is primarily used as a versatile building block and pharmaceutical intermediate in organic synthesis . It has been employed as a starting reagent in the synthesis of 8-methoxy-2-tetralone and in the preparation of di- and tri-substituted 2-oxopiperazines on solid support .
2. 2-Bromophenylacetic acid serves as a key intermediate for creating more complex molecules in medicinal chemistry and material science, leveraging its bromo and carboxylic acid functional groups for further transformations .
3. Applications of 2-Bromophenylacetic acid also include its use in research for palladium-catalyzed coupling reactions and other synthetic methodologies .

1. Store 2-Bromophenylacetic acid CAS 18698-97-0 in a tightly sealed container in a cool, dry, and well-ventilated place . Recommended storage is at ambient temperatures, preferably in a cool and dark place below 15°C , and it should be protected from light as it is light-sensitive .
2. Keep 2-Bromophenylacetic acid away from strong oxidizing agents to prevent hazardous reactions .
3. Always 2-Bromophenylacetic acid use appropriate personal protective equipment (PPE) including protective gloves, eye protection, and face protection when handling 2-Bromophenylacetic acid .

1. Immediately isolate the spill area, ensure adequate ventilation, and contain 2-Bromophenylacetic acid CAS 18698-97-0 using inert, non-combustible absorbent material; prevent material from entering drains or waterways.
2. Carefully sweep up the spilled 2-Bromophenylacetic acid solid using clean methods and place the collected material into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel 2-Bromophenylacetic acid must wear suitable PPE during cleanup. This material and/or its container must be disposed of as hazardous waste .

1. 2-Bromophenylacetic acid CAS 18698-97-0 is classified with GHS signal word "Warning" . It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) . Risk phrases include 36/37/38 (Irritating to eyes, respiratory system and skin) .
2. 2-Bromophenylacetic acid has a melting point of 104-106 °C (lit.) . 2-Bromophenylacetic acid is considered non-hazardous for transport by some regulations, but hazard classifications may vary. Thermal decomposition can produce toxic and irritating fumes including carbon oxides and hydrogen bromide.
3. Always 2-Bromophenylacetic acid CAS 18698-97-0 consult the specific Safety Data Sheet (SDS) for 2-Bromophenylacetic acid for complete hazard information, first-aid procedures, and handling instructions. Precautionary statements include P261 (avoid breathing dust), P280 (wear protective gloves/eye protection), and P405 (store locked up) .