6-Fluoroindole-3-carboxaldehyde CAS 2795-41-7

6-Fluoroindole-3-carboxaldehyde (CAS:2795-41-7) is an important organic raw materials.

Its main applications including:

1. 6-Fluoroindole-3-carboxaldehyde is a key fluorinated indole aldehyde building block for developing central nervous system and anti-tumor small molecule drugs.
2. 6-Fluoroindole-3-carboxaldehyde is a versatile raw material for reductive amination, Knoevenagel condensation and metal-catalyzed coupling synthesis.
3. 6-Fluoroindole-3-carboxaldehyde is a precursor for fluorescent biological probes and nitrogen-containing optoelectronic functional heterocyclic materials.

1. Seal tightly and store below 25°C in dry dark warehouse to prevent photodegradation and oxidation of aldehyde functional group.
2. Reduce frequent package opening to avoid air contact induced discoloration and aldehyde polymerization.
3. Store separately from amines, strong oxidants, strong alkalis and nucleophilic chemical reagents.

1. Avoid inhalation of crystalline dust; wear dust mask and chemical-resistant gloves during weighing and transfer.
2. Never ingest the solid; flush contaminated eyes and skin with abundant running water right after contact.
3. Treat waste residues and filtrate as fluorinated aromatic aldehyde hazardous waste for standardized disposal.

1. Active aldehyde group and 6-position fluorine support condensation, reduction and cross-coupling multi-step derivatization.
2. Stable indole heterocyclic framework adapts to common mild heating and catalytic synthetic conditions.
3. High crystalline purity reduces impurity by-products for targeted heterocyclic pharmaceutical intermediate production.