4-Bromoindole CAS 52488-36-5

4-Bromoindole (CAS:52488-36-5) is an important organic raw materials.

Its main applications including:

1. 4-Bromoindole is a core halogenated indole raw material for synthesis of anti-inflammatory, anticancer and psychiatric pharmaceutical intermediates.
2. 4-Bromoindole is widely used for Suzuki, Buchwald and Heck coupling reactions in fine organic synthesis.
3. 4-Bromoindole is applied to manufacture fluorescent probes, organic optoelectronic materials and indole-based dyestuff precursors.

1. Seal the container tightly and store under 25°C in dry dark warehouse to prevent photodegradation of indole ring.
2. Avoid frequent opening of the package to stop oxidation and discoloration by air.
3. Store separately from strong oxidants, concentrated acids and halogenated reaction reagents.

1. Active C-Br bond at 4-position supports cross-coupling reactions to construct complex aromatic structures.
2. Complete indole heterocyclic framework maintains stability under mild heating synthetic conditions.
3. High crystalline purity reduces impurity generation during preparation of bioactive intermediates.

1. Avoid inhalation of crystalline dust; wear dust mask and chemical resistant gloves during weighing and transfer.
2. Never ingest the solid substance; flush contaminated eyes and skin with plenty of running water immediately.
3. Dispose waste residues and reaction filtrate in accordance with bromo-aromatic hazardous waste standards.