Chlorocyclohexane CAS 542-18-7

1. Chlorocyclohexane is primarily used as an intermediate in organic synthesis for the production of pharmaceuticals, agrochemicals, and rubber chemicals . A notable pharmaceutical application is in the synthesis of the anti-Parkinson's drug trihexyphenidyl (benzhexol) hydrochloride .
2. Chlorocyclohexane CAS 542-18-7 is employed in the manufacturing of pesticides, such as the synthesis of the acaricides cyhexatin and azocyclotin . It also serves as a raw material for producing rubber antiscorching agents .
3. Applications of Chlorocyclohexane include its use as a solvent in organic reactions and in research focused on reaction mechanisms and kinetics .

1. Store Chlorocyclohexane in a tightly sealed container in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames . Recommended storage temperatures range from 0-8 °C to ambient conditions, but it should be kept below 30°C .
2. Keep Chlorocyclohexane strictly away from strong oxidizing agents and strong bases due to incompatibility and the risk of hazardous reactions .
3. Always Chlorocyclohexane CAS 542-18-7 use appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing. Use only with adequate ventilation and avoid breathing vapors .

1. Immediately isolate the spill area and eliminate all ignition sources. Contain Chlorocyclohexane using inert, non-combustible absorbent material (e.g., sand) and prevent entry into drains or waterways .
2. Carefully collect Chlorocyclohexane CAS 542-18-7 into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear suitable PPE including self-contained breathing apparatus (SCBA) during cleanup. Chlorocyclohexane is classified for transport (UN1993, Hazard Class 3, PG III) .

1. Chlorocyclohexane is classified as a flammable liquid (H226) with a flash point of 28°C. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) . It is harmful if swallowed, inhaled, or absorbed through the skin .
2. Chlorocyclohexane may form explosive mixtures with air. Its thermal decomposition or combustion produces toxic and corrosive fumes including carbon monoxide and hydrogen chloride . Acute inhalation toxicity data shows a mouse LC50 of 31,000 mg/m³/2h .
3. Always consult Chlorocyclohexane CAS 542-18-7 the specific Safety Data Sheet (SDS) for Chlorocyclohexane for complete hazard information, first-aid procedures (P303+P361+P353 for skin, P305+P351+P338 for eyes), and handling instructions. Precautionary statements include P210 (keep away from heat/sparks/open flames), P261 (avoid breathing vapors), and P280 (wear protective gloves/eye protection) .