Cyclopropanecarbonitrile CAS 5500-21-0

1. Cyclopropanecarbonitrile is primarily used as a versatile building block and research chemical in organic synthesis, notably to prepare cis- and trans-crotonitrile and allyl cyanide . Cyclopropanecarbonitrile CAS 5500-21-0 also reacts with phenylmagnesium bromide to give cyclopropyl-phenyl ketone-imine .
2. The compound is known as the smallest carbon ring molecule with a cyanide group, making it a subject of interest in experiments involving microwave spectroscopy, rotational spectroscopy, and photodissociation . Cyclopropanecarbonitrile CAS 5500-21-0 was first studied for its rotational spectra in 1958 .
3. Applications of Cyclopropanecarbonitrile also include its use as an impurity standard for the pharmaceutical pazufloxacin mesylate and in chemoselective alkylation studies .

1. Store Cyclopropanecarbonitrile in a tightly sealed container in a cool, dry, and well-ventilated "Flammables area" . Recommended storage temperatures are at room temperature in a cool, dark place (<15°C) or at -20°C for long-term stability . It must be kept away from heat, sparks, and open flames .
2. Keep Cyclopropanecarbonitrile strictly away from strong oxidizing agents, strong reducing agents, strong acids, and strong bases due to its incompatibility with these materials .
3. Always use appropriate Cyclopropanecarbonitrile CAS 5500-21-0 personal protective equipment (PPE) including chemical-resistant gloves, protective clothing, and eye/face protection when handling Cyclopropanecarbonitrile. Use only with adequate ventilation or in a fume hood, and take measures to prevent static discharge .

1. Immediately isolate the spill area, eliminate all ignition sources, and ensure adequate ventilation. Contain Cyclopropanecarbonitrile using inert, non-combustible absorbent material (e.g., dry sand) and prevent entry into drains or waterways .
2. Carefully collect the contaminated material using non-sparking or spark-proof tools and place Cyclopropanecarbonitrile CAS 5500-21-0 into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear full chemical-protective clothing including self-contained breathing apparatus (SCBA) during cleanup. Cyclopropanecarbonitrile is classified for transport (UN3275, Hazard Class 6.1 (3), PG II) as a poisonous and flammable liquid and requires hazardous waste disposal .

1. Cyclopropanecarbonitrile is classified as a dangerous substance (GHS signal word "Danger") that is fatal if swallowed, in contact with skin, or if inhaled (H300+H310+H330) . Cyclopropanecarbonitrile CAS 5500-21-0 is also a flammable liquid and vapour (H226) with a flash point of 32-40°C .
2. Cyclopropanecarbonitrile causes skin irritation (H315) and serious eye irritation (H319), and may cause respiratory irritation (H335) . It is an irritant and can be absorbed through the skin . Cyclopropanecarbonitrile CAS 5500-21-0 is also listed as a chemical asphyxiant .
3. Always consult the specific Safety Data Sheet (SDS) for Cyclopropanecarbonitrile for complete hazard information, first-aid procedures (P301+P310 for ingestion, P303+P361+P353 for skin, P304+P340 for inhalation, P305+P351+P338 for eyes), and handling instructions. Precautionary statements include P210 (keep away from heat/sparks/open flames), P280 (wear protective gloves/eye protection), and P403+P233 (store in well-ventilated place, keep container tightly closed) .