Products Description
Product name: Methoxyacetic anhydride
CAS: 19500-95-9
Density: 1.2±0.1 g/cm ³
Boiling point: 179.6±25.0 °C at 760 mmHg
Molecular formula: C6H10O5
Molecular weight: 162.141
Flash point: 65.4±23.2 °C
Specification
| Items | Specifications |
| Appearance | Colorless and transparent liquid |
| Purity | 99% |
| Storage temp. | 2-8°C |
| Package | 1 kg/bag, 20 kg/drum, 25 kg/drum |
Application
1. Methoxyacetic anhydride is primarily used as a key intermediate in the synthesis of the pharmaceutical decitabine (5-Aza-2'-deoxycytidine), a drug for treating leukemia .
2. Methoxyacetic anhydride CAS 19500-95-9 serves as a versatile acylating agent in organic synthesis to introduce the methoxyacetyl group into various compounds for producing pharmaceuticals, agrochemicals, and other specialty chemicals .
3. Applications of Methoxyacetic anhydride also include its use in esterification and acylation reactions as an acyl donor, where its metabolite methoxyacetic acid has been studied for histone deacetylase (HDAC) inhibition in cancer and teratogenicity research .
Storage and Precautions
1. Store Methoxyacetic anhydride in a tightly sealed container under inert gas (e.g., nitrogen) in a cool, dry place, ideally at -20°C or refrigerated (2-8°C), and strictly protected from moisture .
2. Keep Methoxyacetic anhydride away from strong oxidizing agents, bases, and reducing agents due to incompatibility and potential violent reactions; avoid exposure to light for long-term integrity .
3. Always use Methoxyacetic anhydride CAS 19500-95-9 appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing when handling Methoxyacetic anhydride to avoid contact with this moisture-sensitive and corrosive liquid .
Emergency response to leakage
1. Immediately isolate the spill area, ensure adequate ventilation, and contain Methoxyacetic anhydride using inert, non-combustible absorbent material; prevent entry into drains or waterways .
2. Carefully collect Methoxyacetic anhydride CAS 19500-95-9 using non-sparking tools and place it into a sealed, labeled corrosion-resistant chemical waste container for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear suitable PPE including chemical-protective clothing and self-contained breathing apparatus (SCBA) during cleanup; Methoxyacetic anhydride is classified for transport (UN3265, Hazard Class 8, PG III) as a corrosive liquid .
Safety Information
1. Methoxyacetic anhydride is classified as a corrosive substance (GHS05, Danger) causing severe skin burns and serious eye damage (H314/H318) .
2. Methoxyacetic anhydride is moisture sensitive, very soluble in water (193 g/L at 25°C), and reacts with water to form methoxyacetic acid; its thermal decomposition produces toxic and irritating fumes including carbon oxides .
3. Always consult Methoxyacetic anhydride CAS 19500-95-9 the specific Safety Data Sheet (SDS) for Methoxyacetic anhydride for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P301+P330+P331 for ingestion, P303+P361+P353 for skin), and handling instructions; precautionary statements include P260 (do not breathe vapors), P280 (wear protective gloves/eye protection), and P405 (store locked up) .
Related Product Recommendations
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| 1 | 3-Fluoroaniline CAS 372-19-0 |
| 2 | Ethyl Formate CAS 109-94-4 |
| 3 | 3-Chlorophenylacetic Acid CAS 1878-65-5 |
| 4 | 3-Fluorobenzyl Bromide CAS 456-41-7 |
| 5 | Methyl 3-hydroxybenzoate CAS 19438-10-9 |
| 6 | 3-Chloroperoxybenzoic Acid CAS 937-14-4 |
| 7 | 3-Fluorobenzoic Acid CAS 455-38-9 |
| 8 | 3-Hydroxyphenylacetic Acid CAS 621-37-4 |
| 9 | 3′-Chloroacetophenone CAS 99-02-5 |
| 10 | If you want to need more information,welcome to contact us at any time.
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Packaging




Transportation & Payment

About Transportation
Depending on the requirements of our clients, we can give a variety of transportation options.
For smaller orders, we offer air shipping or international courier services like FedEx, DHL, TNT, EMS, and numerous other unique lines of international transit.
We can transport by sea to a specified port for bigger amounts.
Additionally, we can offer unique services based on the requirements of our clients and the characteristics of their goods.

* We can offer a range of payment options to our clients.
* When the sum is modest, clients typically pay with PayPal, Western Union, Alibaba, and other similar services.
* When the sum is significant, clients typically pay with T/T, L/C at sight, Alibaba, and so on.
* Furthermore, an increasing number of consumers will use Alipay or WeChat Pay to make payments.
FAQ
1
May I get any sample from you?
Re: Yes, of course, we'd like to provide sample to you according to your demands.
2
What is your MOQ?
Re: Usually our MOQ is 1 kg, but sometimes it is also flexible and depends on different products.
3
How long I can get my goods after payment?
Re: If shipped by couriers or air, it usually cost 5-10 days.
If shipped by sea, it usually cost 3-40 days, which depends on your destination.
4
Do you have any after-sales service?
Re: Yes, we will inform you progress of the order, such as product preparation, declaration, transportation follow-up, customs clearance assistance, technical guidance, etc.
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