6-Chloroindole-3-carboxaldehyde CAS 703-82-2

6-Chloroindole-3-carboxaldehyde (CAS:703-82-2) is an important organic heterocyclic pharmaceutical fine intermediates.

Its main applications including:

1. 6-Chloroindole-3-carboxaldehyde is a key functional indole intermediate for synthesis of anticancer, anti-inflammatory and nervous system targeted drugs.
2. 6-Chloroindole-3-carboxaldehyde is a building block for heterocyclic synthesis via aldol condensation, reductive amination and metal-catalyzed coupling reactions.
3. 6-Chloroindole-3-carboxaldehyde is a raw material for biological fluorescent probes, organic functional materials and fine heterocyclic chemical derivatives.

1. Seal tightly and store below 25°C in dry dark warehouse to prevent photodegradation and oxidation of aldehyde groups.
2. Minimize repeated opening of packaging to avoid air-induced oxidation, discoloration and impurity formation.
3. Store separately from strong oxidants, strong alkalis, amines and nucleophilic reagents to prevent side reactions of aldehyde groups.

1. Avoid inhalation of fine crystalline dust; wear dust mask and chemical-resistant gloves during weighing and transfer.
2. Do not ingest the solid; flush contaminated eyes and skin with plenty of running water immediately after accidental contact.
3. Dispose waste residues and filtrate following chlorinated aromatic aldehyde hazardous waste disposal standards.

1. Reactive aldehyde group and C-Cl bond support condensation, reduction and cross-coupling derivatization reactions.
2. Indole heterocyclic core maintains structural stability under conventional mild synthetic reaction conditions.
3. High-purity crystalline material ensures good reaction consistency for heterocyclic drug intermediate synthesis.