6-Chlorooxindole CAS 56341-37-8

6-Chlorooxindole (CAS:56341-37-8) is an important pharmaceutical intermediates.

Its main applications including:

1. 6-Chlorooxindole is a key chloro-substituted oxindole intermediate for antitumor, anti-inflammatory and central nervous system drug synthesis.
2. 6-Chlorooxindole is a substrate for metal-catalyzed cross-coupling reactions in fine organic synthesis for constructing chiral heterocyclic structures.
3. 6-Chlorooxindole is a raw material for research of kinase inhibitors and other targeted small-molecule pharmaceutical precursors.

1. Seal tightly and store below 25°C in dry dark warehouse to prevent photodegradation and oxidative deterioration.
2. Avoid repeated opening of packaging to prevent moisture absorption and discoloration from air exposure.
3. Store separately from strong oxidants, concentrated acids and strong alkaline reagents.

1. Avoid inhalation of fine crystalline dust; wear dust mask and chemical-resistant gloves during weighing and handling.
2. Do not ingest the solid; flush contaminated eyes and skin with plenty of running water immediately after accidental contact.
3. Dispose waste residues and filtrate following chlorinated heterocyclic hazardous waste disposal standards.

1. Reactive C-Cl bond and oxindole core allow diversified coupling and nucleophilic substitution derivatization.
2. Stable lactam heterocyclic framework adapts to common mild heating and catalytic synthesis conditions.
3. High crystalline purity reduces impurity by-products in the synthesis of bioactive heterocyclic compounds.