5-Cyanoindole CAS 15861-24-2

5-Cyanoindole (CAS:15861-24-2) is an important pharmaceutical intermediate.

Its main applications including:

1. 5-Cyanoindole is a key cyano-substituted indole precursor for preparing aminoindole and carboxylic acid indole pharmaceutical intermediates.
2. 5-Cyanoindole is widely used substrate for metal-catalyzed coupling reactions in fine organic synthesis.
3. 5-Cyanoindole is a raw material for synthesizing nitrogen-containing heterocyclic drugs and organic functional chemical products.

1. Seal tightly and store below 25°C in dry dark warehouse to avoid photodegradation of cyano-substituted indole structure.
2. Keep away from impact, friction and high temperature to reduce thermal decomposition risk of cyano functional group.
3. Store separately from strong acids, strong reducing agents and alkaline substances to prevent cyano group hydrolysis and degradation.

1. Avoid inhalation of crystalline dust; wear dust mask and chemical-resistant gloves during weighing and transfer.
2. Do not ingest the solid; flush exposed eyes and skin with abundant running water immediately after contact.
3. Dispose waste residues and filtrate strictly following cyanoaromatic hazardous waste management standards.

1. The cyano group can be easily hydrolyzed, reduced and cyclized for further derivatization of indole derivatives.
2. The indole ring maintains stable structure under normal mild synthesis heating conditions.
3. High purity solid reduces miscellaneous impurities in pharmaceutical intermediate manufacturing routes.