Thiosalicylic Acid CAS 147-93-3

1. Thiosalicylic acid is widely used in pharmaceutical development as an intermediate in the synthesis of drugs for inflammatory and pain-related conditions, and as a precursor to the vaccine preservative thiomersal and drugs for atherosclerosis and melanoma .
2. Thiosalicylic acid CAS 147-93-3 serves as a versatile reagent in organic synthesis, acting as a trapping agent in the desulfenylation of 3-indolyl sulfides and condensing with diamines to prepare macrocyclic diamides .
3. Applications of Thiosalicylic acid also include its use in analytical chemistry for detecting heavy metals, in polymer chemistry as a chain transfer agent, in metal coatings for corrosion resistance, and as a precursor for the thioindigo dyestuff .

1. Store Thiosalicylic acid in a tightly sealed container in a cool, dry, and well-ventilated place, protected from light and air, as it is air and light sensitive . Recommended storage temperatures range from 0-8°C to a cool, dark place below 15°C .
2. Keep Thiosalicylic acid strictly away from strong oxidizing agents to prevent hazardous decomposition .
3. Always Thiosalicylic acid CAS 147-93-3 use appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing when handling Thiosalicylic acid to avoid skin, eye, and respiratory contact .

1. Immediately isolate the spill area, ensure adequate ventilation, and avoid generating dust; contain Thiosalicylic acid using inert, non-combustible absorbent material and prevent entry into drains or waterways .
2. Carefully Thiosalicylic acid CAS 147-93-3 sweep up the spilled Thiosalicylic acid using clean, non-sparking tools, and place the collected material into a sealed, labeled chemical waste container for proper disposal according to local, state, and federal environmental regulations.
3. Personnel must wear suitable PPE including dust mask and gloves during cleanup; Thiosalicylic acid is typically not classified as hazardous goods for transport by some regulations .

1. Thiosalicylic acid is classified with GHS signal word "Warning" and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) . Acute toxicity includes mouse intraperitoneal LD50 of 50 mg/kg .
2. Thiosalicylic acid has a flash point of approximately 150°C and a melting point of 162-168°C . It is soluble in dimethyl sulfoxide, alcohol, ether, and acetic acid, but only slightly soluble in water . Thermal decomposition or combustion produces toxic and irritating fumes including carbon oxides and sulfur oxides.
3. Always Thiosalicylic acid CAS 147-93-3 consult the specific Safety Data Sheet (SDS) for Thiosalicylic acid for complete hazard information, first-aid procedures (P305+P351+P338 for eyes, P302+P352 for skin), and handling instructions; precautionary statements include P280 (wear protective gloves/eye protection) .