3-Cyanopyridine CAS 100-54-9

1. 3-Cyanopyridine is a heterocyclic building block primarily used as a key intermediate in the synthesis of pharmaceuticals, including the antituberculosis drug isoniazid and other nicotinic acid derivatives .
2. 3-Cyanopyridine CAS 100-54-9 serves as a versatile precursor in organic synthesis for the preparation of nicotinamide, niacin (vitamin B3), and various agrochemicals .
3. 3-Cyanopyridine is employed in the synthesis of pyridine-based ligands for coordination chemistry and as a building block for functional materials and fine chemicals .
4. Researchers utilize 3-Cyanopyridine CAS 100-54-9 as a reference standard in analytical chemistry and as a starting material for the preparation of heterocyclic compounds with potential biological activities .

1. 3-Cyanopyridine must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at room temperature in a cool, dark place .
2. 3-Cyanopyridine CAS 100-54-9 is classified with GHS hazard statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H332 (Harmful if inhaled), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep 3-Cyanopyridine CAS 100-54-9 away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when 3-Cyanopyridine is released .
2. Collect 3-Cyanopyridine CAS 100-54-9 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. 3-Cyanopyridine is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 3-Cyanopyridine CAS 100-54-9 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 3-Cyanopyridine due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .