DL-Sulforaphane CAS 4478-93-7

1. DL-Sulforaphane is a potent inducer of phase II detoxification enzymes with anticarcinogenic properties, functioning by activating the Keap1/Nrf2/ARE pathway to enhance cellular antioxidant capacity and promote the transcription of tumor suppressor proteins .
2. DL-Sulforaphane CAS 4478-93-7 is extensively used in cancer research to study the inhibition of tumor cell proliferation, induction of apoptosis, and suppression of metastasis across multiple cancer types including prostate, breast, lung, and colon cancers .
3. DL-Sulforaphane serves as a research tool for investigating anti-inflammatory mechanisms, where it suppresses the LPS-mediated expression of pro-inflammatory cytokines such as iNOS, COX-2, IL-1β, and TNF-α .
4. In metabolic and neurological research, DL-Sulforaphane is employed to study its effects on insulin resistance, lipid metabolism, neuroinflammation, and potential therapeutic applications in conditions such as obesity, diabetes, and neurodegenerative diseases .

1. DL-Sulforaphane must be stored in a tightly sealed container at -20°C, protected from light and moisture, as it is light-sensitive and moisture-sensitive .
2. For solution storage, dissolve in DMSO (40 mg/mL soluble) and prepare aliquots to avoid repeated freeze-thaw cycles; long-term exposure to air should be minimized to prevent degradation .
3. Personnel DL-Sulforaphane CAS 4478-93-7 must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling DL-Sulforaphane, as it causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) .
4. Store under inert atmosphere (nitrogen or argon) to maintain stability, and keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable respirator when DL-Sulforaphane is released .
2. For liquid spills, collect DL-Sulforaphane CAS 4478-93-7 using non-sparking tools by absorbing with inert materials such as sand, diatomite, or universal binders, and place into suitable closed containers for disposal .
3. Avoid creating vapors or mists during cleanup to prevent respiratory exposure; no special environmental precautions are required, but discharge into drains should be prevented .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. DL-Sulforaphane is a combustible liquid with an NFPA fire rating of 3, indicating it can be ignited under almost all ambient temperature conditions .
2. Use water spray, alcohol-resistant foam, dry chemical powder, or carbon dioxide to extinguish fires involving the product; do NOT use a direct water jet as DL-Sulforaphane CAS 4478-93-7 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning DL-Sulforaphane due to hazardous decomposition gases .
4. Hazardous decomposition products formed under fire conditions include toxic fumes of carbon monoxide, carbon dioxide, nitrogen oxides (NOx), and sulfur oxides; contain fire runoff to prevent environmental contamination .