3-Hydroxy-N-Methyl-3-Phenyl-Propylamine CAS 42142-52-9

1. 3-Hydroxy-N-methyl-3-phenyl-propylamine is a key pharmaceutical intermediate used in the synthesis of the antidepressant drug fluoxetine (Prozac) hydrochloride and the attention deficit hyperactivity disorder (ADHD) medication atomoxetine (Strattera) .
2. 3-Hydroxy-N-Methyl-3-Phenyl-Propylamine CAS 42142-52-9 serves as an aromatic amino alcohol used as an initiator in radical addition reactions with tetrahalomethanes for organic synthesis applications .
3. In pharmaceutical research, this compound is recognized as an impurity standard for fluoxetine, making it valuable for quality control and analytical method development in drug manufacturing .
4. 3-Hydroxy-N-Methyl-3-Phenyl-Propylamine CAS 42142-52-9 is utilized in the synthesis of heterocyclic systems and serves as a building block for various nitrogen-containing organic compounds in medicinal chemistry research .

1. 3-Hydroxy-N-methyl-3-phenyl-propylamine must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light; recommended storage at room temperature in an inert atmosphere or in a dark place .
2. 3-Hydroxy-N-Methyl-3-Phenyl-Propylamine CAS 42142-52-9 is classified with GHS hazard statement H302 (Harmful if swallowed), with signal word "Warning" and hazard symbol GHS07 .
3. Personnel must wear chemical-resistant gloves (meeting EN 374 standards), safety glasses with side-shields conforming to EN166, and impervious protective clothing when handling this substance. Use dust masks when handling large quantities .
4. Keep away from incompatible materials such as strong oxidizing agents to prevent decomposition. Avoid dust formation and ensure adequate ventilation in work areas .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and dust respirator when cleaning up the compound .
2. Collect 3-Hydroxy-N-Methyl-3-Phenyl-Propylamine CAS 42142-52-9 by sweeping or vacuuming without creating dust, using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; do not let the product enter drains, sewers, or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration. Contaminated packaging should be triply rinsed and offered for recycling or disposed of in a sanitary landfill .

1. 3-Hydroxy-N-methyl-3-phenyl-propylamine is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides .
2. Use 3-Hydroxy-N-Methyl-3-Phenyl-Propylamine CAS 42142-52-9 water spray, alcohol-resistant foam, dry chemical powder, or carbon dioxide to extinguish fires involving the product .
3. Firefighters should wear self-contained breathing apparatus (SCBA) in pressure-demand, NIOSH-approved, and full protective gear when handling fires involving this compound due to hazardous decomposition gases generated during thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination. Discharge into the environment must be avoided .