4-Bromobiphenyl CAS 92-66-0

1. 4-Bromobiphenyl is a versatile building block in organic synthesis used to introduce the biphenyl moiety into more complex molecules, particularly in the synthesis of pharmaceuticals, agrochemicals, and organic materials .
2. 4-Bromobiphenyl serves as a key intermediate in the preparation of liquid crystals, where biphenyl derivatives are essential components for display technologies .
3. 4-Bromobiphenyl is employed in the synthesis of flame retardants, heat transfer agents, and as a precursor for the production of biphenyl-based polymers .
4. In research applications, 4-bromobiphenyl is used in cross-coupling reactions such as Suzuki-Miyaura and Negishi couplings to construct biaryl systems for drug discovery and materials science .

1. 4-Bromobiphenyl must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at room temperature in a cool, dark place .
2. 4-Bromobiphenyl CAS 92-66-0 is classified with GHS hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep 4-Bromobiphenyl CAS 92-66-0 away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when 4-Bromobiphenyl is released .
2. Collect 4-Bromobiphenyl CAS 92-66-0 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. 4-Bromobiphenyl is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and hydrogen bromide .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 4-Bromobiphenyl CAS 92-66-0 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 4-Bromobiphenyl due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .