4-nitroindole CAS 4769-97-5

4-nitroindole (CAS:4769-97-5) is an important active pharmaceutical ingredient intermediate.

Its main applications including:

1. 4-nitroindole is a key nitro-substituted indole precursor for preparing aminoindole pharmaceutical intermediates.
2. 4-nitroindole is widely used substrate for metal-catalyzed coupling reactions in fine organic synthesis.
3. 4-nitroindole is a raw material for synthesizing organic fluorescent probes and nitrogen-containing heterocyclic functional chemicals.

1. Seal tightly and store below 25°C in dry dark warehouse to avoid photodegradation of nitro-indole structure.
2. Keep away from impact, friction and high temperature to reduce thermal decomposition risk of nitro group.
3. Store separately from strong reducing agents, combustible materials and concentrated strong acids.

1. Avoid inhalation of crystalline dust; wear dust mask and chemical-resistant gloves during weighing and transfer.
2. Do not ingest the solid; flush exposed eyes and skin with abundant running water immediately after contact.
3. Dispose waste residues and filtrate strictly following nitroaromatic hazardous waste management standards.

1. Nitro group can be easily reduced to amino group for further derivatization of indole derivatives.
2. The indole ring maintains stable structure under normal mild synthesis heating conditions.
3. High purity solid reduces miscellaneous impurities in pharmaceutical intermediate manufacturing routes.