N-(Pyridin-3-ylmethyl)ethanamine CAS 3000-75-7

1. N-(Pyridin-3-ylmethyl)ethanamine is primarily used as a reagent in organic synthesis, particularly for preparing bis-nicotine derivatives that act as inhibitors of cholinesterases and β-amyloid aggregation in neurodegenerative disease research .
2. N-(Pyridin-3-ylmethyl)ethanamine CAS 3000-75-7 serves as a key intermediate in the synthesis of [11C]EMPA, a potential PET tracer for orexin 2 receptors used in neuroimaging studies .
3. N-(Pyridin-3-ylmethyl)ethanamine functions as a versatile building block for developing pharmaceuticals, agrochemicals, pyridine derivatives, ligands, and specialty amine-based compounds .
4. The amino-methyl-pyridine scaffold enables diverse coupling and substitution reactions, supporting efficient synthesis of functional molecules for drug discovery and chemical biology research .

1. N-(Pyridin-3-ylmethyl)ethanamine must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment under inert atmosphere (nitrogen or argon) at 2-8°C or at -20°C for long-term stability .
2. N-(Pyridin-3-ylmethyl)ethanamine CAS 3000-75-7 is classified with GHS hazard statements H302 (Harmful if swallowed), H314 (Causes severe skin burns and eye damage), and H335 (May cause respiratory irritation), with some notifications indicating H315, H317, and H319 .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, face protection, and appropriate protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents and strong acids/bases to prevent decomposition, and wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, remove all sources of ignition, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and appropriate respiratory protection when N-(Pyridin-3-ylmethyl)ethanamine is released .
2. Collect N-(Pyridin-3-ylmethyl)ethanamine CAS 3000-75-7 using non-sparking tools by sweeping or vacuuming without creating dust, or absorb with inert materials (diatomite, universal binders), and place into suitable closed containers for disposal .
3. Avoid creating dust or vapor clouds during cleanup to prevent respiratory exposure, decontaminate surfaces using appropriate methods, and prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration, as the substance has UN classification 6.1 and packing group III .

1. N-(Pyridin-3-ylmethyl)ethanamine has a boiling point of approximately 217.5±15.0°C at 760 mmHg and density of 0.967 g/cm³, and may decompose under fire conditions emitting toxic fumes including carbon oxides and nitrogen oxides .
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product, selecting appropriate extinguishing media based on surrounding environment .
3. Firefighters N-(Pyridin-3-ylmethyl)ethanamine CAS 3000-75-7 should wear self-contained breathing apparatus and full protective gear when handling burning N-(Pyridin-3-ylmethyl)ethanamine due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray, and contain fire runoff to prevent environmental contamination and pollution .