5-Bromoindole -3-carboxaldehyde CAS 877-03-2

5-Bromoindole -3-carboxaldehyde (CAS:877-03-2) is an important pharmaceutical intermediates.

Its main applications including:

1. 5-Bromoindole -3-carboxaldehyde is a key bromo and aldehyde disubstituted indole precursor for preparing high-activity indole pharmaceutical intermediates.
2. 5-Bromoindole -3-carboxaldehyde is widely used dual-functional substrate for metal-catalyzed coupling and aldehyde-based modification reactions in fine organic synthesis.
3. 5-Bromoindole -3-carboxaldehyde is a core raw material for synthesizing nitrogen heterocyclic bioactive compounds and organic functional fluorescent molecules.

1. Seal tightly and store below 25°C in dry dark warehouse to avoid photodegradation and aldehyde oxidation deterioration.
2. Keep away from high temperature and heat sources to prevent thermal decomposition of bromoaryl and aldehyde functional groups.
3. Store separately from strong oxidants, strong reducing agents and alkaline substances to avoid structural damage and side reactions.

1. Avoid inhalation of crystalline dust; wear dust mask and chemical-resistant gloves during weighing and transfer.
2. Do not ingest the solid; flush exposed eyes and skin with abundant running water immediately after contact.
3. Dispose waste residues and filtrate strictly following halogenated aromatic aldehyde hazardous waste management standards.

1. Active aldehyde group can undergo condensation, reduction and addition reactions for diversified derivatization of indole skeletons.
2. The bromo substituent and indole ring maintain stable structure under normal mild synthesis heating conditions.
3. High purity solid reduces miscellaneous impurities in complex heterocyclic drug intermediate synthesis routes.