5-Bromoindole CAS 10075-50-0

5-Bromoindole (CAS:10075-50-0) is an important pharmaceutical intermediates.

Its main applications including:

1. 5-Bromoindole is a key bromo-substituted indole precursor for preparing functionalized indole pharmaceutical intermediates and bioactive molecules.
2. 5-Bromoindole is widely used substrate for metal-catalyzed coupling reactions in fine organic synthesis.
3. 5-Bromoindole is a raw material for synthesizing nitrogen-containing heterocyclic drugs, organic fluorescent materials and fine chemical products.

1. Seal tightly and store below 25°C in dry dark warehouse to avoid photolysis and dehalogenation of bromoindole structure.
2. Keep away from impact, friction and high temperature to reduce thermal decomposition risk of aromatic bromide structure.
3. Store separately from strong reducing agents, active metals and concentrated strong acids to prevent debromination reactions.

1. Avoid inhalation of crystalline dust; wear dust mask and chemical-resistant gloves during weighing and transfer.
2. Do not ingest the solid; flush exposed eyes and skin with abundant running water immediately after contact.
3. Dispose waste residues and filtrate strictly following halogenated aromatic hazardous waste management standards.

1. The bromo substituent serves as an excellent leaving group for efficient cross-coupling and further derivatization of indole derivatives.
2. The indole ring maintains stable structure under normal mild synthesis heating conditions.
3. High purity solid reduces miscellaneous impurities in pharmaceutical intermediate manufacturing routes.