Ethoxyquin CAS 91-53-2

1. Ethoxyquin CAS 91-53-2 is a synthetic antioxidant primarily used as a preservative in animal feed (for poultry, livestock, and farmed fish) and canned pet food to prevent lipid peroxidation and stabilize fat-soluble vitamins.
2. In food industry applications, it serves as a preservative for fruits and vegetables by forming a protective film that inhibits oxidation, reduces moisture loss, and extends shelf life during long-distance transportation .
3. Ethoxyquin functions as a chain-breaking antioxidant that inhibits azo-initiated peroxidation, with research demonstrating it inhibits peroxidation as efficiently as α-tocopherol but with more than 2-fold longer inhibition time .
4. In biomedical research, ethoxyquin is studied as a cancer chemopreventive agent that induces phase II drug-metabolizing enzymes (glutathione S-transferases) through the Nrf2 transcription factor pathway, protecting against carcinogenesis .

1. Ethoxyquin CAS 91-53-2 must be stored in a tightly sealed container under inert atmosphere (nitrogen) at refrigerated temperatures (2-8°C) and protected from light, as it polymerizes and darkens on exposure to light and air .
2. Ethoxyquin is classified with GHS hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H335 (May cause respiratory irritation), and H413 (May cause long-lasting adverse effects to aquatic life) .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, face protection, and protective clothing when handling this substance, ensuring adequate ventilation in work areas (preferably a chemical fume hood) .
4. Keep Ethoxyquin away from incompatible materials such as strong oxidizing agents and strong acids; avoid exposure to heat above 320°F where hazardous polymerization may occur .

1. Isolate the spill area, ensure adequate ventilation, remove all sources of ignition, and wear full personal protective equipment including NIOSH/MSHA-approved respirator with organic vapor cartridges when ethoxyquin is released .
2. Collect Ethoxyquin by using absorbent paper to pick up all liquid spill material; seal contaminated clothing and absorbent paper in vapor-tight plastic bags for eventual disposal .
3. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution; avoid creating vapors during cleanup and prevent product from entering drains or water courses .
4. Dispose of collected Ethoxyquin material as hazardous waste according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. Ethoxyquin CAS 91-53-2 is combustible with a flash point of 225°F (138°C) and may undergo hazardous polymerization at temperatures above 320°F; under fire conditions, hazardous decomposition products include toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product; do NOT use a direct water jet as Ethoxyquin may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning ethoxyquin due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray from a protected location, and contain fire runoff to prevent environmental contamination .