L-Pyroglutamic Acid CAS 98-79-3

1. L-Pyroglutamic acid is an endogenous cyclic amino acid derivative that serves as a key intermediate in the gamma-glutamyl cycle and is used as a building block in pharmaceutical synthesis for drugs targeting cognitive function and neuroprotection .
2. L-Pyroglutamic acid CAS 98-79-3 is employed in cosmetic formulations as a humectant and moisturizing agent due to its excellent water-binding properties, where it enhances skin hydration and improves product texture .
3. L-Pyroglutamic acid functions as a chiral synthon in organic synthesis for preparing optically active compounds, including peptides, amino acid derivatives, and other biologically active molecules .
4. Researchers utilize L-Pyroglutamic acid CAS 98-79-3 as a reference standard in analytical chemistry and as a research tool for studying glutamatergic neurotransmission, particularly its role in modulating neurotransmitter release and synaptic plasticity .

1. L-Pyroglutamic acid must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at -20°C for long-term stability (up to 3 years) or at 4°C for up to 2 years .
2. L-Pyroglutamic acid CAS 98-79-3 is classified with GHS hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas and avoiding formation of dust and aerosols .
4. Keep L-Pyroglutamic acid CAS 98-79-3 away from incompatible materials such as strong oxidizing agents to prevent decomposition; for solution storage, prepare aliquots and use within 1 month at -20°C, avoiding repeated freeze-thaw cycles .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when L-Pyroglutamic acid is released .
2. Collect L-Pyroglutamic acid CAS 98-79-3 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses as discharge into the environment should be avoided .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. L-Pyroglutamic acid is not classified as highly flammable (NFPA fire rating of 1) with a melting point of 158-162°C; under fire conditions, hazardous decomposition products include toxic fumes of carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as L-Pyroglutamic acid CAS 98-79-3 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning L-Pyroglutamic acid due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, and contain fire runoff to prevent environmental contamination .