Cyclopropyl Methyl Ketone CAS 765-43-5

1. Cyclopropyl methyl ketone CAS 765-43-5 is used as a chemical intermediate for the manufacturing of pharmaceuticals, agrochemicals, and other organic compounds, including use in the preparation of homoallylic alcohols .
2. Cyclopropyl methyl ketone serves as a reagent in the synthesis of PDE4 inhibitors and α-trifluoromethyl-amines, and plays a role in the synthesis of complex organic molecules through ring-opening reactions .
3. Applications of Cyclopropyl methyl ketone also include its use in the synthesis of δ-ketonic phosphonium salts for Wittig reactions and in research focused on its unique reactivity due to the strained cyclopropane ring .

1. Store Cyclopropyl methyl ketone CAS 765-43-5 in a tightly sealed container in a cool, dry, and well-ventilated area, away from heat, sparks, open flames, and direct sunlight, as Cyclopropyl methyl ketone is a highly flammable liquid . Recommended storage is in a flammable materials area or in a cool, dark place .
2. Keep Cyclopropyl methyl ketone strictly away from strong oxidizing agents, strong acids, and strong bases due to incompatibility and the risk of violent reactions .
3. Always use appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing. Use only with adequate ventilation or in a fume hood, and employ spark-proof tools and explosion-proof equipment to prevent ignition from.

1. Immediately isolate the spill area (minimum 50 meters), eliminate all ignition sources, and evacuate non-essential personnel. Contain Cyclopropyl methyl ketone CAS 765-43-5 using dry, inert, non-combustible absorbent material (e.g., dry sand or universal binder) and prevent entry into drains or waterways .
2. Carefully collect Cyclopropyl methyl ketone using non-sparking, explosion-proof tools into sealed, labeled chemical waste containers for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must Cyclopropyl methyl ketone wear full chemical-protective equipment including self-contained breathing apparatus (SCBA) during cleanup. Cyclopropyl methyl ketone is classified for transport as a flammable liquid.

1. Cyclopropyl methyl ketone CAS 765-43-5 is classified as a highly flammable liquid and vapor (H225, Danger) with a flash point ranging from 13°C to 21°C (55-70°F), and may form explosive mixtures with air .
2. Cyclopropyl methyl ketone is toxic if swallowed (H301) with a reported mouse oral LD50 of 185 mg/kg, causes skin irritation (H315), serious eye irritation (H319), and may be harmful if inhaled . Its vapors are heavier than air and may travel to distant ignition sources, causing flashback .
3. Always consult Cyclopropyl methyl ketone the specific Safety Data Sheet (SDS) for Cyclopropyl methyl ketone for complete hazard information, first-aid procedures, and handling instructions. Precautionary statements include P210 (keep away from heat/sparks/open flames), P233 (keep container tightly closed), P240 (ground/bond container), and P280 (wear protective gloves/eye protection) .