Dichloroacetyl Chloride CAS 79-36-7

1. Dichloroacetyl chloride is primarily used as a reactive intermediate in organic synthesis, notably as a reagent for the mild acetylation of whole plant cell walls to facilitate structural analysis via NMR .
2. Dichloroacetyl chloride CAS 79-36-7 serves as a key raw material in the synthesis of vinyl-based insecticides and finds application in industrial processes such as wool felt fulling, bleaching, and disinfection .
3. Applications of Dichloroacetyl chloride also include its use in biomedical research as a strong electrophile for targeted drug delivery strategies, enabling highly localized tissue necrosis in liver models .

1. Store Dichloroacetyl chloride in a tightly sealed container under an inert atmosphere in a cool, dry, and well-ventilated area, strictly protected from moisture and water as it decomposes upon contact . Recommended storage is in a cool, dry place away from sunlight .
2. Keep Dichloroacetyl chloride strictly away from strong oxidizing agents, strong bases, alcohols, and metal powders due to incompatibility and the risk of violent reactions, including the generation of flammable hydrogen gas . Containers must be grounded/bonded to prevent electrostatic discharge.
3. Always use Dichloroacetyl chloride CAS 79-36-7 appropriate personal protective equipment (PPE) including chemical-resistant gloves, tightly fitting safety goggles with a faceshield, and chemical-protective clothing. Handle only in a fume hood with adequate ventilation to avoid breathing vapors, as it is corrosive and a lachrymator .

1. Immediately isolate the spill area (minimum 50 meters/150 feet for large spills), eliminate all ignition sources, and evacuate non-essential personnel. For spills in water, toxic and corrosive hydrogen chloride gas may be produced, requiring initial isolation of 100 ft and protective action distances of 0.1-0.3 miles downwind depending on spill size .
2. Contain Dichloroacetyl chloride using dry, inert, non-combustible absorbent material (e.g., dry sand). DO NOT use water. Carefully collect the contaminated material using non-sparking tools into sealed, labeled corrosion-resistant chemical waste containers for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must Dichloroacetyl chloride CAS 79-36-7 wear full chemical-protective equipment including self-contained breathing apparatus (SCBA) during cleanup. Dichloroacetyl chloride is classified for transport (UN1765, Hazard Class 8, Packing Group II) and requires hazardous waste disposal.

1. Dichloroacetyl chloride is classified as a corrosive substance (GHS05, Danger), causing severe skin burns and serious eye damage (H314/H318) . It is very toxic to aquatic life (H400/H410) . Rat oral LD50 is 2.46 g/kg .
2. Dichloroacetyl chloride is a combustible liquid (flash point 66°C) with an autoignition temperature of 585°C and explosive limits of 11.9% in air . It reacts violently with water, releasing toxic and corrosive hydrogen chloride gas, and thermal decomposition produces toxic fumes including phosgene and carbon oxides . Vapors are heavier than air (vapor density 5.1) .
3. Dichloroacetyl chloride CAS 79-36-7 has a boiling point of 107-110°C and density of 1.53 g/cm³ . Always consult the specific Safety Data Sheet (SDS) for Dichloroacetyl chloride for complete hazard information, first-aid procedures (P303+P361+P353 for skin, P305+P351+P338 for eyes, P301+P330+P331 for ingestion, P304+P340 for inhalation), and handling instructions .