Fluorobenzene CAS 462-06-6

1. Fluorobenzene is a critical intermediate in pharmaceutical synthesis, used to produce antipsychotic drugs (e.g., trifluoperazine, fluphenazine) and fluoroquinolone antibiotics (e.g., ciprofloxacin) . Fluorobenzene CAS 462-06-6 also serves as a key building block for manufacturing agrochemicals including pesticides, herbicides, and larvicides .
2. The compound is utilized in producing high-performance engineering plastics like polyetherketones for aerospace and automotive applications, and as an additive in lithium batteries to improve safety and efficiency . Fluorobenzene CAS 462-06-6 also contributes to synthesizing materials for electronic components and advanced semiconductors .
3. Applications of Fluorobenzene include its use as a reagent for identifying plastic or resin polymers , as a versatile solvent in organic synthesis , and in the production of fluorinated polymers known for chemical resistance and durability .

1. Store Fluorobenzene in a tightly sealed container in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames . Recommended storage temperatures range from 0-8°C to 0-6°C , with some sources indicating ambient storage (>5°C) for certain solutions .
2. Keep Fluorobenzene strictly away from strong oxidizing agents due to incompatibility and risk of violent reactions . Grounding and bonding of containers is required to prevent electrostatic discharge as vapors may form explosive mixtures with air .
3. Always use Fluorobenzene CAS 462-06-6 appropriate personal protective equipment (PPE) including chemical-resistant gloves (Viton® or butyl-rubber recommended), tightly fitting safety goggles with faceshield, and flame-retardant antistatic protective clothing . Handle only with explosion-proof equipment in a fume hood to avoid breathing vapors .

1. Immediately isolate the spill area (at least 50 meters/150 feet in all directions), eliminate all ignition sources, and evacuate non-essential personnel . Contain Fluorobenzene using dry, inert, non-combustible absorbent material (e.g., dry sand or universal binder) and prevent entry into drains or waterways .
2. Carefully collect Fluorobenzene CAS 462-06-6 using non-sparking, explosion-proof tools into sealed, labeled chemical waste containers . A vapor-suppressing foam may be used to reduce vapors, and water spray may reduce vapor but may not prevent ignition in closed spaces .
3. Personnel must wear full chemical-protective equipment including self-contained breathing apparatus (SCBA) during cleanup . Fluorobenzene is classified for transport (UN2387, Hazard Class 3, PG II) and requires hazardous waste disposal according to local, state, and federal environmental regulations.

1. Fluorobenzene is classified as a highly flammable liquid and vapor (H225, Danger) with a flash point ranging from -15°C to -12.8°C (5-9°F), and forms explosive mixtures with air (LEL 1.3%, UEL 8.9%) . It causes serious eye irritation (H319/H318), skin irritation (H315), and may cause damage to organs (H370) .
2. Fluorobenzene is harmful if swallowed (LD50 oral rat: 4,399 mg/kg), inhaled (LC50 rat: 26,908 mg/L), or absorbed through the skin . It is toxic to aquatic life with long-lasting effects (H412/H411) . Burning in open flame can form toxic hydrogen fluoride gases, and vapors are heavier than air (vapor density 3.31) and may travel to distant ignition sources causing flashback .
3. Chronic inhalation Fluorobenzene CAS 462-06-6 of vapors may result in damage to lungs, liver, and kidneys; acute exposure can cause symptoms ranging from coughing to transient anesthesia and central nervous system depression . Always consult the specific Safety Data Sheet (SDS) for Fluorobenzene for complete hazard information, first-aid procedures (P301+P310 for ingestion, P303+P361+P353 for skin, P305+P351+P338 for eyes, P304+P340 for inhalation), and handling instructions .