2 2-Diphenylacetic Acid CAS 117-34-0

1. 2,2-Diphenylacetic acid is widely utilized as a key intermediate in the synthesis of various pharmaceuticals, enhancing the efficiency of drug formulation processes . It serves as a reagent in the kinetic resolution of racemic compounds, such as 2-hydroxy-γ-butyrolactone .
2. 2 2-Diphenylacetic acid CAS 117-34-0 is valuable in organic synthesis as a building block for creating complex molecules, including its use as an additive in ruthenium-catalyzed arylation reactions and as a catalyst in Rh-catalyzed coupling reactions .
3. Applications of 2,2-Diphenylacetic acid also include its use in the production of specialty polymers for industries like automotive and electronics, and as a standard in analytical chemistry for chromatography .

1. Store 2,2-Diphenylacetic acid in a tightly sealed container in a cool, dry, and well-ventilated area away from incompatible substances . Recommended storage conditions vary from room temperature (sealed in a dry place) to refrigeration at 0-8°C .
2. Keep 2,2-Diphenylacetic acid away from strong oxidizing agents, strong acids, and strong bases to prevent decomposition or hazardous reactions.
3. Always use 2 2-Diphenylacetic acid CAS 117-34-0 appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing; avoid dust formation and ensure adequate ventilation when handling the powder .

1. Immediately isolate the spill area and ensure adequate ventilation. Contain 2,2-Diphenylacetic acid using dry, inert, non-combustible absorbent material and prevent entry into drains or waterways.
2. Carefully sweep up 2 2-Diphenylacetic acid CAS 117-34-0 using clean, non-sparking tools, avoiding dust generation, and place the collected material into sealed, labeled chemical waste containers for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear suitable PPE including chemical-resistant gloves and eye protection during cleanup. 2,2-Diphenylacetic acid is classified as non-hazardous for transport by some regulations (RIDADR: NONH for all modes of transport) .

1. 2,2-Diphenylacetic acid is classified as an irritant (Xi, GHS signal word "Warning") . It causes skin irritation (R36/38, H315) and serious eye irritation (H319) .
2. Acute toxicity 2 2-Diphenylacetic acid CAS 117-34-0 data shows oral LD50 values of 5540 mg/kg in rats and 3200 mg/kg in mice, with observed effects including changes in motor activity and ataxia . Intraperitoneal LD50 in mice is 500 mg/kg, and subcutaneous LD50 is 400 mg/kg .
3. Under fire conditions, thermal decomposition or combustion of 2,2-Diphenylacetic acid produces toxic and irritating fumes, including carbon oxides. The compound has a melting point range of 146-149°C and a flash point of 140°C . Always consult the specific Safety Data Sheet (SDS) for complete hazard information and first-aid procedures (P305+P351+P338 for eyes, P302+P352 for skin).