Sulfolane CAS 126-33-0

1. Sulfolane is primarily used as a specialized, high-purity solvent in the petrochemical industry for the extractive distillation of aromatic hydrocarbons like benzene, toluene, and xylene from refinery streams .Sulfolane CAS 126-33-0 is also employed in natural gas processing to remove acid gases (sour gas sweetening) .
2. The compound serves as a versatile solvent in the electronics sector for manufacturing circuit board cleaners , and is increasingly important as a component in lithium-ion battery electrolyte formulations . Sulfolane CAS 126-33-0 is also utilized as a solvent for polymers, in pharmaceutical reactions, and in paints, coatings, and inks .
3. Applications of Sulfolane also include its role in organic synthesis as a reaction medium and as a plasticizer . Its high chemical and thermal stability make it suitable for demanding industrial processes where traditional solvents like NMP (N-Methyl-2-pyrrolidone) may pose higher health risks .

1. Store Sulfolane in a tightly sealed container in a cool, dry, and well-ventilated area, away from heat, sparks, and open flames. Recommended storage temperatures range from 2-8°C to ambient, and it should be kept separate from oxidizing agents .
2. Keep Sulfolane strictly away from strong oxidizing agents (such as chlorosulfonic acid and oleum) and strong bases to prevent violent reactions or hazardous decomposition .
3. Always use Sulfolane CAS 126-33-0 appropriate personal protective equipment (PPE) including safety goggles with a faceshield, chemical-resistant gloves (e.g., chloroprene or nitrile), and protective clothing when handling Sulfolane to avoid skin, eye, and respiratory contact. Handle only with adequate ventilation .

1. Immediately isolate the spill area (at least 50 meters for liquids), eliminate all ignition sources, and ensure adequate ventilation. Contain Sulfolane using dry, inert, non-combustible absorbent material (e.g., sand) and prevent entry into drains or waterways as it is water-soluble and can contaminate groundwater .
2. Carefully collect Sulfolane CAS 126-33-0 using non-sparking tools or an explosion-proof vacuum into sealed, labeled chemical waste containers. For small spills, absorbent material can be used; for large spills, dike far ahead of the liquid .
3. Personnel must wear full chemical-protective equipment including self-contained breathing apparatus (SCBA) during cleanup. Dispose of Sulfolane and all contaminated materials according to local, state, and federal environmental regulations, as it is not classified as hazardous waste for transport by some regulations (UN/NA Number is Class 9) .

1. Sulfolane is classified as a combustible liquid (flash point 166-177°C) . Sulfolane CAS 126-33-0 is harmful if swallowed (H302, H302+H332), may cause eye irritation (H319) and mild skin irritation, and is suspected of damaging fertility or the unborn child (H361) according to GHS classification .
2. Sulfolane is very water-soluble and has been identified as a groundwater contaminant near industrial sites, leading to concerns about human exposure through drinking water . Thermal decomposition or combustion produces toxic and irritating fumes, including carbon oxides, sulfur oxides, and hydrogen sulfide . The NFPA health rating is 1 (can cause significant irritation), flammability 1 (must be preheated), and reactivity 0 (normally stable) .
3. Always consult Sulfolane CAS 126-33-0 the specific Safety Data Sheet (SDS) for Sulfolane for complete hazard information, first-aid procedures (P301+P330+P331 for ingestion, P305+P351+P338 for eyes), and handling instructions. Precautionary statements include P201 (obtain special instructions before use), P202 (do not handle until all safety precautions read), P280 (wear protective gloves/eye protection), and P308+P313 (if exposed or concerned) . The U.S. National Toxicology Program (NTP) has ongoing studies to evaluate its chronic toxicity and potential carcinogenic effects .