3-Methyl-4-nitrophenol CAS 2581-34-2

1. 3-Methyl-4-nitrophenol CAS 2581-34-2 is widely utilized as a key intermediate in the chemical industry, most notably for the synthesis of the organophosphate insecticide fenitrothion.
2. 3-Methyl-4-nitrophenol serves as a biochemical reagent in research focused on environmental decontamination, where it is used to study the biodegradation and chemotaxis of microorganisms like *Ralstonia* sp. SJ98, which can utilize it as a sole carbon source .
3. 3-Methyl-4-nitrophenol is employed in pharmaceutical development for preparing intermediates, such as phosphorothioamidate analogues investigated as potential antimalarial agents .
4. Researchers utilize 3-Methyl-4-nitrophenol in toxicological and environmental monitoring studies to investigate its effects, which include anti-androgenic activity and potential mutagenicity, and to detect pollutants in samples .

1. 3-Methyl-4-nitrophenol CAS 2581-34-2 must be stored in a tightly sealed container in a cool, dry, and well-ventilated area, with recommended storage temperatures between 0-8°C, and kept away from strong oxidizing agents .
2. 3-Methyl-4-nitrophenol CAS 2581-34-2 is classified with acute toxicity hazards, being harmful if swallowed (H302), in contact with skin (H312), or if inhaled (H332). It also causes skin (H315) and serious eye irritation (H319) .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas (preferably a chemical fume hood) .
4. Avoid 3-Methyl-4-nitrophenol formation of dust and aerosols, wash thoroughly after handling, and follow precautionary statements.

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including suitable respirator when 3-Methyl-4-nitrophenol CAS 2581-34-2 is released .
2. Collect 3-Methyl-4-nitrophenol by sweeping or vacuuming without creating dust, or absorb with inert materials such as sand or diatomite using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure, and prevent the product from entering drains or water courses due to potential environmental hazards .
4. Dispose of collected material as hazardous waste according to local, state, and federal environmental regulations .

1. 3-Methyl-4-nitrophenol CAS 2581-34-2 is combustible with a flash point of approximately 110°C, and under fire conditions may decompose to emit toxic fumes including carbon oxides and nitrogen oxides .
2. Use dry 3-Methyl-4-nitrophenol chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product; do NOT use water jet as it may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus and full protective gear when handling burning 3-Methyl-4-nitrophenol due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray, and contain fire runoff to prevent environmental contamination and pollution .