Cordycepin CAS 73-03-0

1. Cordycepin is primarily used in biomedical research as a cytotoxic nucleoside analogue for its broad spectrum of therapeutic potential, including anti-cancer, anti-inflammatory, anti-oxidative, and anti-metastatic activities, with applications in studying neoplasms and metabolic disorders such as hyperlipidemia and diabetes .
2. Cordycepin CAS 73-03-0 functions as an anticancer and antifungal agent by converting to 3'-deoxyadenosine triphosphate (3'-dATP) within cells, which inhibits ATP-dependent DNA synthesis, disrupts RNA polyadenylation, and modulates multiple signaling pathways including MAPK, ERK, PI3K, AKT, and NF-κB to induce apoptosis and cell cycle arrest in various tumor cells .
3. Cordycepin is employed in pharmacological research for its nephroprotective effects against renal ischemia/reperfusion injury, where it significantly decreases serum blood urea nitrogen and creatinine levels while regulating inflammation, apoptosis, and oxidative stress in experimental models .
4. Researchers Cordycepin CAS 73-03-0 utilize this product in drug delivery studies, where encapsulation in liposomes, polymeric nanoparticles, or emulsomes enhances its bioavailability, stability, and targeted delivery to overcome its short half-life and sensitivity to adenosine deaminase (ADA) enzymes .

1. Cordycepin must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment protected from light and moisture; in lyophilized powder form, it is stable for up to 3 years at -20°C or 2 years at 4°C, while solutions should be stored at -80°C for up to 6 months or -20°C for 1 month .
2. Cordycepin CAS 73-03-0 is classified with hazard statements H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with a signal word "Danger" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, impervious protective clothing, and suitable respirators when handling cordycepin, ensuring adequate ventilation in work areas (preferably a chemical fume hood) and avoiding dust and aerosol formation .
4. Avoid inhalation, contact Cordycepin CAS 73-03-0 with eyes and skin; keep away from incompatible materials such as strong acids/alkalis, strong oxidizing agents, and strong reducing agents; for solution storage, prepare aliquots in tightly sealed vials and use within recommended timeframes to prevent potency loss .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable respirator when cordycepin is released, evacuating personnel to safe areas .
2. Collect Cordycepin CAS 73-03-0 by sweeping or vacuuming without creating dust, using non-sparking tools; absorb solutions with finely-powdered liquid-binding materials such as diatomite or universal binders, and place into suitable closed containers for disposal .
3. Avoid creating dust or vapor clouds during cleanup to prevent respiratory exposure, decontaminate surfaces and equipment by scrubbing with alcohol, and prevent Cordycepin CAS 73-03-0 from entering drains or water courses due to potential environmental hazards .
4. Dispose of collected material according to local, state, and federal environmental regulations, as runoff from fire control or dilution water may cause pollution; conduct recycling or disposal in accordance with prevailing country, federal, state, and local regulations .

1. Cordycepin is not classified as highly flammable (NFPA fire rating of 1) but may decompose under fire conditions, emitting toxic fumes including nitrogen oxides, carbon monoxide, carbon dioxide, and irritating gases generated by thermal decomposition or combustion .
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product, selecting appropriate extinguishing media based on surrounding environment .
3. Firefighters Cordycepin CAS 73-03-0 should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning cordycepin due to hazardous decomposition gases and to prevent contact with skin and eyes .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray, and contain fire runoff to prevent environmental contamination and pollution .