4-Hydroxycoumarin CAS 1076-38-6

1. 4-Hydroxycoumarin is a heterocyclic compound primarily used as the key precursor for the synthesis of the anticoagulant drug warfarin and other 4-hydroxycoumarin-based anticoagulants such as acenocoumarol and phenprocoumon .
2. 4-Hydroxycoumarin CAS 1076-38-6 serves as a versatile building block in medicinal chemistry for the preparation of antimicrobial, antifungal, anticancer, and anti-inflammatory agents .
3. 4-Hydroxycoumarin is employed in the synthesis of fluorescent dyes, optical brighteners, and as a scaffold for developing enzyme inhibitors .
4. In agricultural chemistry, 4-hydroxycoumarin is used as a precursor for the synthesis of rodenticides and plant growth regulators .

1. 4-Hydroxycoumarin must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light and moisture; recommended storage at 2-8°C or at room temperature in a cool, dark place .
2. 4-Hydroxycoumarin CAS 1076-38-6 is classified with GHS hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Warning" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, and protective clothing when handling this substance, ensuring adequate ventilation in work areas .
4. Keep 4-Hydroxycoumarin CAS 1076-38-6 away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases to prevent decomposition; wash thoroughly after handling .

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable dust respirator when 4-Hydroxycoumarin is released .
2. Collect 4-Hydroxycoumarin CAS 1076-38-6 by sweeping or vacuuming without creating dust using non-sparking tools, and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure; prevent the product from entering drains or water courses .
4. Dispose of collected material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration .

1. 4-Hydroxycoumarin is not classified as highly flammable but may decompose under fire conditions, emitting toxic fumes including carbon monoxide, carbon dioxide, and nitrogen oxides (NOx) .
2. Use water spray, dry chemical powder, carbon dioxide, or alcohol-resistant foam to extinguish fires involving the product; do NOT use a direct water jet as 4-Hydroxycoumarin CAS 1076-38-6 may scatter burning material .
3. Firefighters should wear self-contained breathing apparatus in pressure-demand, MSHA/NIOSH approved, and full protective gear when handling burning 4-Hydroxycoumarin due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; contain fire runoff to prevent environmental contamination .