4-Ethoxybenzoic Acid CAS 619-86-3

1. 4-Ethoxybenzoic acid is widely utilized in pharmaceutical research for its anti-biofilm activity, inhibiting up to 87% of *Staphylococcus aureus* biofilm formation and potentiating biofilm sensitivity to vancomycin by altering cell membrane hydrophobicity . It also serves as an intermediate in the synthesis of various pharmaceuticals, enhancing drug efficacy and stability .
2. 4-Ethoxybenzoic acid CAS 619-86-3 is used in polymer chemistry for the production of specialty polymers and in material science for preparing highly conducting and flexible few-walled carbon nanotube thin films .
3. Applications of 4-Ethoxybenzoic acid also include its role as a building block in organic synthesis, a reagent in analytical procedures, and as an ester component in photoaffinity labeling studies of nicotinic acetylcholine receptors .

1. Store 4-Ethoxybenzoic acid in a tightly sealed container in a cool, dry, and well-ventilated place at ambient room temperature, protected from light . Stock solutions prepared in DMSO should be stored at -20°C for short-term use or -80°C for longer periods .
2. Keep 4-Ethoxybenzoic acid away from strong oxidizing agents, strong acids, and strong bases to prevent decomposition or hazardous reactions. It is stable under normal temperatures and pressures.
3. Always use 4-Ethoxybenzoic acid CAS 619-86-3 appropriate personal protective equipment (PPE) including chemical-resistant gloves (e.g., nitrile) and safety goggles when handling 4-Ethoxybenzoic acid to avoid dust generation and contact with skin and eyes .

1. Immediately isolate the spill area and ensure adequate ventilation. Contain 4-Ethoxybenzoic acid using dry, inert, non-combustible absorbent material (e.g., sand) and prevent entry into drains or waterways .
2. Carefully sweep 4-Ethoxybenzoic acid CAS 619-86-3 up the spilled solid using clean, non-sparking tools, avoiding dust generation, and place the collected material into sealed, labeled chemical waste containers for proper disposal according to local, state, and federal environmental regulations .
3. Personnel must wear suitable PPE including chemical-resistant gloves and eye protection during cleanup. 4-Ethoxybenzoic acid is not classified as hazardous goods for transport by some regulations .

1. 4-Ethoxybenzoic acid is classified with GHS signal word "Warning" . It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335) . 4-Ethoxybenzoic acid CAS 619-86-3 is also classified as harmful if swallowed (H302) by some sources .
2. 4-Ethoxybenzoic acid has a melting point of 195-201°C and appears as a white crystalline powder . It is combustible, and thermal decomposition or combustion can produce toxic and irritating fumes, including carbon monoxide .
3. Always consult the specific Safety Data Sheet (SDS) for 4-Ethoxybenzoic acid for complete hazard information and first-aid procedures (P305+P351+P338 for eyes, P302+P352 for skin, P304+P340 for inhalation). Precautionary statements include P261 (avoid breathing dust), P280 (wear protective gloves/eye protection), and P405 (store locked up) .