3-Hydroxyisoquinoline CAS 7651-81-2

1. 3-Hydroxyisoquinoline CAS 7651-81-2 is primarily used as a key intermediate in pharmaceutical synthesis, particularly for developing drugs targeting neurological disorders, where its unique structure enables improved efficacy and reduced side effects .
2. 3-Hydroxyisoquinoline serves as a versatile building block in organic synthesis for creating complex heterocyclic compounds and as a ligand in coordination chemistry, with applications in producing dyes, agrochemicals, and specialty chemicals .
3. 3-Hydroxyisoquinoline is employed in biological research as a fluorescent probe for imaging applications, where its fluorescence properties enable visualization of cellular components; studies in invertebrate models demonstrate intense blue fluorescence localized in cell nuclei .
4. Researchers utilize 3-Hydroxyisoquinoline in material science for developing polymers and coatings requiring specific chemical properties, and in the synthesis of bioactive compounds with potential antimicrobial and anticancer activities .

1. 3-Hydroxyisoquinoline CAS 7651-81-2 must be stored in a tightly sealed container in a cool, dry, and well-ventilated environment, protected from light; recommended storage temperatures range from room temperature (inert atmosphere) to 2-8°C or -20°C for long-term stability .
2. 3-Hydroxyisoquinoline is classified with GHS hazard statements H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation), with signal word "Danger" .
3. Personnel must wear chemical-resistant gloves, safety goggles with side-shields, face protection, and protective clothing when handling 3-Hydroxyisoquinoline, ensuring adequate ventilation in work areas (preferably a chemical fume hood) and avoiding formation of dust and aerosols .
4. Keep 3-Hydroxyisoquinoline away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents; wash thoroughly after handling, and follow precautionary statements.

1. Isolate the spill area, ensure adequate ventilation, and wear full personal protective equipment including chemical-resistant gloves, safety goggles, and suitable respirator when 3-Hydroxyisoquinoline CAS 7651-81-2 is released, evacuating personnel to safe areas .
2. Collect 3-Hydroxyisoquinoline by sweeping or vacuuming without creating dust using non-sparking tools; for small spills, use appropriate containment methods and place into suitable closed containers for disposal .
3. Avoid creating dust clouds during cleanup to prevent respiratory exposure, and prevent the product from entering drains or water courses due to potential environmental hazards, as discharge into the environment must be avoided .
4. Dispose of collected 3-Hydroxyisoquinoline material according to local, state, and federal environmental regulations through licensed chemical destruction or controlled incineration with flue gas scrubbing, following UN transport guidelines for toxic solids .

1. 3-Hydroxyisoquinoline is not classified as highly flammable but may decompose under fire conditions, with a flash point of 68-319.4°C reported across sources, emitting toxic fumes including nitrogen oxides and carbon oxides when involved in a fire .
2. Use dry chemical powder, carbon dioxide, alcohol-resistant foam, or water spray to extinguish fires involving the product, selecting appropriate extinguishing media based on surrounding environment .
3. Firefighters 3-Hydroxyisoquinoline CAS 7651-81-2 should wear self-contained breathing apparatus and full protective gear when handling burning 3-Hydroxyisoquinoline due to hazardous decomposition gases generated by thermal decomposition .
4. During combustion, may emit irritant and toxic fumes; move containers from the fire area if safe to do so, cool exposed containers with water spray, and contain fire runoff to prevent environmental contamination and pollution .